Release of eIF4E from the inactive eIF4E:4E-BP complex

Stable Identifier
R-HSA-72622
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Release of eIF4E from the inactive eIF4E:4E-BP complex
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
eIF4E gets released from the inactive eIF4E:4EBP complex.
Literature References
PubMed ID Title Journal Year
7935836 Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.

Lin, TA, Lawrence, JC, Gingras, AC, Pause, A, Sonenberg, N, Donzé, O, Belsham, GJ

Nature 1994
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Orthologous Events
Release of eIF4E from the inactive eIF4E:4E-BP complex (Bos taurus)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Canis familiaris)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Danio rerio)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Dictyostelium discoideum)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Drosophila melanogaster)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Gallus gallus)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Mus musculus)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Rattus norvegicus)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Sus scrofa)
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