Cytosolic aldolase catalyzes the cleavage of D-fructose 1,6-bisphosphate to yield dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. The active form of aldolase is a homotetramer. Three aldolase isozymes have been identified which differ in their patterns of expression in various adult tissues and during development but are otherwise functionally indistinguishable (Ali and Cox 1995; Freemont et al. 1984, 1988).
Cox, TM, Ali, M
Dunbar, B, Freemont, PS, Fothergill, LA
Dunbar, B, Fothergill-Gilmore, LA
fructose-bisphosphate aldolase activity of aldolase tetramer [cytosol]
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