D-methylmalonyl-CoA <=> L-methylmalonyl-CoA

Stable Identifier
R-HSA-71020
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At the beginning of this reaction, 1 molecule of 'D-methylmalonyl-CoA' is present. At the end of this reaction, 1 molecule of 'L-methylmalonyl-CoA' is present.

This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'methylmalonyl-CoA epimerase activity' of 'methylmalonyl-CoA epimerase'.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
11481338 Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome.

Bobik, TA, Rasche, ME

J Biol Chem 2001
13934211 Metabolism of propionic acid in animal tissues. IX. Methylmalonyl coenzyme A racemase

Sasakawa, T, Ochoa, S, Mazumder, R, Kaziro, Y

J Biol Chem 1962
Participants
Participates
Catalyst Activity

methylmalonyl-CoA epimerase activity of MCEE [mitochondrial matrix]

Orthologous Events
Cross References
Rhea
Cite Us!