D-methylmalonyl-CoA <=> L-methylmalonyl-CoA

Stable Identifier
R-HSA-71020
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'D-methylmalonyl-CoA' is present. At the end of this reaction, 1 molecule of 'L-methylmalonyl-CoA' is present.

This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'methylmalonyl-CoA epimerase activity' of 'methylmalonyl-CoA epimerase'.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
11481338 Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome.

Bobik, TA, Rasche, ME

J Biol Chem 2001
13934211 Metabolism of propionic acid in animal tissues. IX. Methylmalonyl coenzyme A racemase

Sasakawa, T, Ochoa, S, Mazumder, R, Kaziro, Y

J Biol Chem 1962
Participants
Participates
Catalyst Activity

methylmalonyl-CoA epimerase activity of MCEE [mitochondrial matrix]

Orthologous Events
Cross References
Rhea
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