Propionyl-CoA catabolism

Stable Identifier
R-HSA-71032
Type
Pathway
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Propionyl-CoA catabolism
Click the image above or here to open this pathway in the Pathway Browser
Propionyl-CoA is a product of the catabolism of the amino acids, leucine, methionine, and threonine, and of the beta-oxidation of fatty acids with odd numbers of carbon atoms. The three reactions of this pathway convert propionyl-CoA to succinyl-CoA, an intermediate of the citric acid cycle. Through these reactions, carbon atoms from these sources can be fully oxidized to produce energy, or can be directed to gluconeogenesis. The three reactions of propionyl-CoA catabolism take place in the mitochondrial matrix.
Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
short-chain fatty acid catabolic process (0019626)
Orthologous Events
Propionyl-CoA catabolism (Bos taurus)
Propionyl-CoA catabolism (Caenorhabditis elegans)
Propionyl-CoA catabolism (Canis familiaris)
Propionyl-CoA catabolism (Danio rerio)
Propionyl-CoA catabolism (Dictyostelium discoideum)
Propionyl-CoA catabolism (Gallus gallus)
Propionyl-CoA catabolism (Mus musculus)
Propionyl-CoA catabolism (Rattus norvegicus)
Propionyl-CoA catabolism (Sus scrofa)
Propionyl-CoA catabolism (Xenopus tropicalis)
Authored
Cite Us!