Reactome | PXLP-K69-ODC1 [cytosol]

PXLP-K69-ODC1 [cytosol]

Stable Identifier

R-HSA-70689

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ODC, ornithine decarboxylase

Locations in the PathwayBrowser

Expand all

Literature References

PubMed ID	Title	Journal	Year
	The Metabolic and Molecular Bases of Inherited Disease, 8th ed Beaudet, AL, Scriver, CR, Sly, WS, Valle, D		2001

External Reference Information

External Reference

UniProt:P11926 ODC1

Gene Names

ODC1

Chain

chain:1-461

Reference Genes

BioGPS Gene:4953 ODC1

COSMIC (genes):ODC1 ODC1

CTD Gene:4953 ODC1

dbSNP Gene:4953 ODC1

ENSEMBL:ENSG00000115758 ODC1

ENSEMBL:ENSG00000115758.14 ODC1

HGNC:8109 ODC1

KEGG Gene (Homo sapiens):4953 ODC1

Monarch:4953 ODC1

NCBI Gene:4953 ODC1

OMIM:165640 ODC1

UCSC:P11926 ODC1

Reference Transcript

Other Identifiers

1081_at

11752515_a_at

16894402

200790_PM_at

200790_at

2540162

2540163

2540164

2540166

2540167

2540169

2540171

2540172

2540173

2540174

2540175

2540176

2540178

2540180

2540189

2540190

2540191

2540192

2540193

2540194

36203_at

4953

8050240

A_23_P165840

GE59733

GO:0001822

GO:0003824

GO:0004586

GO:0005515

GO:0005575

GO:0005737

GO:0005829

GO:0006520

GO:0006595

GO:0006596

GO:0008283

GO:0008284

GO:0009615

GO:0016829

GO:0016830

GO:0016831

GO:0030163

GO:0033387

GO:0042176

GO:0042803

GO:0048856

HMNXSV003046623

ILMN_1748591

M33764_at

PH_hs_0025897

TC02001570.hg

g4505488_3p_at

Participates

as a component of

as an input of

Inferred To

wu:fc54f04 [cytosol] (Danio rerio)

azin2 [cytosol] (Xenopus tropicalis)

PXLP-K69-ODC1 [cytosol] (Bos taurus)

PXLP-K69-ODC1 [cytosol] (Caenorhabditis elegans)

PXLP-K69-ODC1 [cytosol] (Canis familiaris)

PXLP-K69-ODC1 [cytosol] (Dictyostelium discoideum)

PXLP-K69-ODC1 [cytosol] (Drosophila melanogaster)

PXLP-K69-ODC1 [cytosol] (Gallus gallus)

PXLP-K69-ODC1 [cytosol] (Mus musculus)

PXLP-K69-ODC1 [cytosol] (Plasmodium falciparum)

PXLP-K69-ODC1 [cytosol] (Rattus norvegicus)

PXLP-K69-ODC1 [cytosol] (Saccharomyces cerevisiae)

PXLP-K69-ODC1 [cytosol] (Schizosaccharomyces pombe)

PXLP-K69-ODC1 [cytosol] (Sus scrofa)

Modified Residues

Name

N6-pyridoxal phosphate-L-lysine at 69

Coordinate

PsiMod Name

N6-pyridoxal phosphate-L-lysine [MOD:00128]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.

Cross References

RefSeq

NP_001274118.1, NP_001274119.1, NP_002530.1

Guide to Pharmacology - Targets

1276

OpenTargets

ENSG00000115758

ZINC - Substances

DCOR_HUMAN

ZINC target

P11926

ZINC - Biogenic

DCOR_HUMAN

PRO

P11926

PDB

7U6U, 7S3G, 2ON3, 7U6P, 5BWA, 1D7K, 2OO0, 7S3F, 4ZGY

ZINC - Metabolites

DCOR_HUMAN

HPA

ENSG00000115758-ODC1

GeneCards

P11926

Ensembl

ENSP00000390691, ENSP00000385333, ENSG00000115758, ENST00000234111, ENSP00000514633, ENSP00000234111, ENST00000699835, ENST00000699836, ENSP00000514634, ENST00000443218, ENST00000405333

Pharos - Targets

P11926

ZINC - Predictions - Purchasable

DCOR_HUMAN

Orphanet

28274

HMDB Protein

HMDBP01034

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H8Y8 GORASP2	2	GORASP2 [Golgi membrane] (R-HSA-2422385) p-T222,T225-GORASP2 [Golgi membrane] (R-HSA-2422965)	0.781	11
UniProt:Q9UMX2 OAZ3	1	OAZ3 [cytosol] (R-HSA-350586)	0.743	5
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.718	6
UniProt:Q9UMX2-2 OAZ3			0.556	3

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