L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate

Stable Identifier
R-HSA-70655
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
L-glutamate 5-semialdehyde => (S)-1-pyrroline-5-carboxylate + H(+) + H2O
ReviewStatus
5/5
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L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The interconversion of glutamate 5-semialdehyde (L-GluSS) and (S)-1-pyrroline-5-carboxylate (1PYR-5COOH) is a spontaneous reaction (Scriver et al. 2001).
Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
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Event Information
Reverse Reaction
1PYR-5COOH spontaneously hydrolyses to L-GluSS (Homo sapiens)
Cross References
Rhea
Reviewed
D'Eustachio, P  (2024-11-08)
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