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G2 Phase
Stable Identifier
R-HSA-68911
DOI
10.3180/REACT_1915.2
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2 Phase (Homo sapiens)
General
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This is one of two 'gap' phases in the standard eukaryotic mitotic cell cycle. It is the interval between the completion of DNA synthesis and the beginning of mitosis. Protein synthesis occurs in this phase, following DNA replication in the S phase. This is the time when the cell stockpiles on the cytoplasmic contents, before mitosis and cytokinesis occur (Mitchison 2003, Kaldis 2016).
Literature References
PubMed ID
Title
Journal
Year
12921238
Growth during the cell cycle
Mitchison, JM
Int. Rev. Cytol.
2003
27626033
Quo Vadis Cell Growth and Division?
Kaldis, P
Front Cell Dev Biol
2016
Participants
Events
Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3
(Homo sapiens)
Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)
(Homo sapiens)
Participates
as an event of
Mitotic G2-G2/M phases (Homo sapiens)
Event Information
Go Biological Process
regulation of mitotic cell cycle (0007346)
Orthologous Events
G2 Phase (Bos taurus)
G2 Phase (Canis familiaris)
G2 Phase (Drosophila melanogaster)
G2 Phase (Gallus gallus)
G2 Phase (Mus musculus)
G2 Phase (Rattus norvegicus)
G2 Phase (Sus scrofa)
G2 Phase (Xenopus tropicalis)
Cross References
BioModels Database
BIOMD0000000723
,
BIOMD0000000939
,
BIOMD0000000660
,
BIOMD0000000700
Created
Walworth, N (2003-06-05)
O'Donnell, M (2003-06-05)
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