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RPA4 [nucleoplasm]
Stable Identifier
R-HSA-68566
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA Replication factor A protein 4 (30kD), Replication protein A 30 kDa subunit, RP-A, RF-A, Replication factor-A protein 4
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1/S Transition (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
DNA polymerase epsilon binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
DNA polymerase epsilon binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA4 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13156 RPA4
Gene Names
RPA4
Chain
chain:1-261
Reference Genes
BioGPS Gene:29935 RPA4
COSMIC - genes:RPA4 RPA4
CTD Gene:29935 RPA4
dbSNP Gene:29935 RPA4
ENSEMBL:ENSG00000204086 RPA4
HGNC:30305 RPA4
KEGG:hsa:29935 RPA4
Monarch:29935 RPA4
NCBI Gene:29935 RPA4
OMIM:300767 RPA4
UCSC:Q13156 RPA4
Reference Transcript
RefSeq:NM_013347.4 RPA4
Other Identifiers
11732061_at
17105315
221143_PM_at
221143_at
29935
3984126
3984127
3984128
3984129
8168723
A_23_P254212
GE80878
GO:0000077
GO:0000724
GO:0000781
GO:0003677
GO:0003697
GO:0005515
GO:0005634
GO:0005654
GO:0005662
GO:0006260
GO:0006270
GO:0006281
GO:0006289
GO:0006310
GO:0006974
GO:0035861
GO:0042162
HMNXSV003052569
ILMN_1798880
PH_hs_0034873
TC0X000465.hg
U24186_at
g9558730_3p_at
Participates
as a component of
RPA1-4 [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of RPA4 [nucleoplasm]
(Bos taurus)
Ghost homologue of RPA4 [nucleoplasm]
(Canis familiaris)
Ghost homologue of RPA4 [nucleoplasm]
(Mus musculus)
Ghost homologue of RPA4 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of RPA4 [nucleoplasm]
(Sus scrofa)
Ghost homologue of RPA4 [nucleoplasm]
(Xenopus tropicalis)
RPA2 [nucleoplasm]
(Drosophila melanogaster)
RPA2 [nucleoplasm]
(Gallus gallus)
ssb2 [nucleoplasm]
(Schizosaccharomyces pombe)
RFA2 [nucleoplasm]
(Saccharomyces cerevisiae)
rpa2 [nucleoplasm]
(Danio rerio)
Cross References
RefSeq
NP_037479.1
ENSEMBL
ENSG00000204086
,
ENST00000373040
,
ENSP00000362131
OpenTargets
ENSG00000204086
GeneCards
RPA4
HPA
ENSG00000204086-RPA4
PRO
Q13156
Pharos - Targets
Q13156
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27694 RPA1
2
RPA1 [nucleoplasm]
(R-HSA-68461)
polySUMO2,3-K449,K577-RPA1 [nucleoplasm]
(R-HSA-4551644)
0.744
8
UniProt:Q9Y5B9 SUPT16H
1
SUPT16H [nucleoplasm]
(R-HSA-112415)
0.527
3
UniProt:Q01831 XPC
5
XPC [nucleoplasm]
(R-HSA-67441)
Ub-XPC [nucleoplasm]
(R-HSA-6782944)
Ub,SUMO-XPC [nucleoplasm]
(R-HSA-6790460)
Ub,SUMO,K63polyUb-XPC [nucleoplasm]
(R-HSA-6790522)
monoSUMO1-K655-XPC [nucleoplasm]
(R-HSA-4570458)
0.527
3
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