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SUPT16H

Stable Identifier
R-HSA-112415
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
FACT 140 kDa subunit
Locations in the PathwayBrowser
Summation

DSIF is a heterodimer consisting of hSPT4 (human homolog of yeast Spt4- p14) and hSPT5 (human homolog of yeast Spt5-p160). DSIF association with Pol II may be enabled by Spt5 binding to Pol II creating a scaffold for NELF binding (Wada et al.,1998). Spt5 subunit of DSIF can be phosphorylated by P-TEFb.

External Reference Information
External Reference
Gene Names
SUPT16H, FACT140, FACTP140
Chain
initiator methionine:1, chain:2-1047
Reference Transcript
Other Identifiers
0006520037
11198
11717114_a_at
16790267
217815_at
22551
233827_s_at
49787
4Z2M
4Z2N
57040_at
5E5B
68143_at
7977674
A_23_P151634
A_24_P153800
AAD43978
AAF28231
AAH00565
AAH14046
AAH64561
AAH73849
AF152961
AF164924
BC000565
BC014046
BC064561
BC073849
CAB022551
CCDS9569
ENSG00000092201
ENSP00000216297
ENST00000216297
EntrezGene:11198
g6005756_3p_at
GE58441
GO:0003674
GO:0003723
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0006259
GO:0006260
GO:0006281
GO:0006337
GO:0006351
GO:0006355
GO:0006366
GO:0006368
GO:0006950
GO:0006974
GO:0007165
GO:0008150
GO:0009058
GO:0031491
GO:0032786
GO:0032968
GO:0034641
GO:0034724
GO:0035101
GO:0042393
GO:0043226
GO:0043234
GO:0051276
GO:1901796
HGNC:11465
HPA049787
Hs.14963.1.S1_3p_a_at
Hs.213724
ILMN_1781516
IPR000640
IPR000994
IPR013719
IPR013953
IPR029148
IPR029149
MIM:605012
NM_007192
NP_009123
PF00557
PF08512
PF08644
PF14826
PH_hs_0028053
SM01285
SM01286
SM01287
SUPT16H
SUPT16H-201
TC14000916.hg
uc001wao.2
UPI0000035D5C
XM_011536381
XP_011534683
Participant Of
Inferred To
Cross References
RefSeq
GeneCards
DOCK Blaster
PRO
PDB