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Unfolded GBA [cytosol]
Stable Identifier
R-HSA-6813790
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Association of TriC/CCT with target proteins during biosynthesis (Homo sapiens)
Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) (Homo sapiens)
CCT/TRiC:substrate complex [cytosol] (Homo sapiens)
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
Unfolded GBA [cytosol] (Homo sapiens)
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
Unfolded GBA [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04062 GBA1
Gene Names
GBA1, GBA, GC, GLUC
Chain
signal peptide:1-39, chain:40-536
Reference Genes
BioGPS Gene:2629 GBA1
COSMIC (genes):GBA GBA1
COSMIC (genes):GC GBA1
CTD Gene:2629 GBA1
dbSNP Gene:2629 GBA1
ENSEMBL:ENSG00000177628 GC
HGNC:4177 GBA1
KEGG:hsa:2629 GBA1
Monarch:2629 GBA1
NCBI Gene:2629 GBA1
OMIM:606463 GBA1
UCSC:P04062 GBA1
Reference Transcript
RefSeq:NM_000157.3 GBA1
RefSeq:NM_001005742.2 GBA1
RefSeq:NM_001171811.1 GBA1
RefSeq:NM_001005741.2 GBA1
RefSeq:NM_001171812.1 GBA1
Other Identifiers
11719908_a_at
11736100_a_at
11748292_a_at
11750975_x_at
11751085_a_at
11751086_x_at
11751098_a_at
11751099_x_at
11753439_a_at
11753440_x_at
11754819_x_at
16694064
209093_PM_s_at
209093_s_at
210589_PM_s_at
210589_s_at
2437207
2437208
2437209
2437210
2437213
2437214
2437215
2437217
2437219
2437221
2437222
2437223
2437224
2437226
2437229
2437233
2437236
2437249
2437250
2437251
2437252
2437253
2437254
2437255
2437256
2437257
2437258
2437259
2437260
2437261
2437262
2437263
2437264
2437265
2437266
2437268
2437269
2437270
2437271
2437272
2629
32631_at
32632_g_at
40889_at
43836_s_at
7920697
A_23_P201035
GE80897
GO:0000423
GO:0002376
GO:0003824
GO:0004336
GO:0004348
GO:0005102
GO:0005124
GO:0005515
GO:0005615
GO:0005764
GO:0005765
GO:0005773
GO:0005783
GO:0005794
GO:0005802
GO:0006091
GO:0006629
GO:0006665
GO:0006678
GO:0006680
GO:0006914
GO:0007005
GO:0007040
GO:0007417
GO:0008203
GO:0008340
GO:0008422
GO:0009267
GO:0009268
GO:0012501
GO:0014004
GO:0016020
GO:0016241
GO:0016740
GO:0016757
GO:0016787
GO:0016798
GO:0019882
GO:0019915
GO:0021694
GO:0021859
GO:0022904
GO:0023021
GO:0030154
GO:0030163
GO:0030259
GO:0031333
GO:0032006
GO:0032436
GO:0032715
GO:0033077
GO:0033574
GO:0035307
GO:0042391
GO:0043161
GO:0043202
GO:0043226
GO:0043243
GO:0043407
GO:0043524
GO:0043627
GO:0046512
GO:0046513
GO:0046527
GO:0048469
GO:0048854
GO:0048856
GO:0048870
GO:0048872
GO:0050295
GO:0050728
GO:0050877
GO:0050905
GO:0051246
GO:0051248
GO:0051402
GO:0061436
GO:0061518
GO:0061744
GO:0070062
GO:0071356
GO:0071425
GO:0071548
GO:0072676
GO:0097066
GO:0098773
GO:1901135
GO:1901805
GO:1903052
GO:1903061
GO:1904457
GO:1904925
GO:1905037
GO:1905165
HMNXSV003032524
HMNXSV003050815
ILMN_1741837
ILMN_1755123
ILMN_2364110
J03060_at
PH_hs_0030649
PH_hs_0034252
TC01003308.hg
TC01006304.hg
g183021_3p_a_at
g496370_3p_a_at
Participates
as a candidate of
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
Other forms of this molecule
GBA1 [lysosomal membrane]
Cross References
ZINC - World Drugs
GLCM_HUMAN
Guide to Pharmacology - Targets
2978
OpenTargets
ENSG00000177628
ENSEMBL
ENST00000427500
,
ENSP00000397986
,
ENSP00000314508
,
ENST00000428024
,
ENSP00000402577
,
ENST00000327247
,
ENSP00000357357
,
ENST00000368373
ZINC - Substances
GLCM_HUMAN
ZINC - Biogenic
GLCM_HUMAN
ZINC target
P04062
PRO
P04062
GlyGen
P04062
PDB
6YTR
,
3GXD
,
3RIK
,
6Q6L
,
6Q6K
,
6TJQ
,
3GXM
,
8AWR
,
3GXF
,
3RIL
,
3GXI
,
6T13
,
6TN1
,
5LVX
,
2VT0
,
1OGS
,
6YV3
,
2XWE
,
1Y7V
,
2XWD
,
2NSX
,
8P3E
,
6Q6N
,
8AX3
,
6Q1N
,
2WCG
,
3KEH
,
6Q1P
,
7NWV
,
3KE0
,
2NT0
,
2NT1
,
6MOZ
,
2V3E
,
2WKL
,
6Z39
,
6YUT
,
2V3D
,
6Z3I
,
2F61
,
6TJK
,
2V3F
,
2J25
,
8P41
,
6YTP
,
8AWK
,
6TJJ
ZINC - Investigational
GLCM_HUMAN
ZINC - Metabolites
GLCM_HUMAN
HPA
ENSG00000177628-GBA1
Pharos - Targets
P04062
Orphanet
GBA1
ZINC - Predictions - Purchasable
GLCM_HUMAN
HMDB Protein
HMDBP01795
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27824 CANX
2
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
0.527
2
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