Reactome | KRTAP4-11 [cytosol]

KRTAP4-11 [cytosol]

Stable Identifier

R-HSA-6809960

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 4-11, KR411_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP4s [cytosol] (Homo sapiens)
        
        KRTAP4-11 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP4s [cytosol] (Homo sapiens)
        
        KRTAP4-11 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BYQ6 KRTAP4-11

Gene Names

KRTAP4-11, KAP4.14, KRTAP4-14, KRTAP4.11, KRTAP4.14

Chain

chain:1-195

Reference Genes

BioGPS Gene:653240 KRTAP4-11

COSMIC (genes):KRTAP4-11 KRTAP4-11

CTD Gene:653240 KRTAP4-11

dbSNP Gene:653240 KRTAP4-11

ENSEMBL:ENSG00000212721 KRTAP4-11

HGNC:18911 KRTAP4-11

Monarch:653240 KRTAP4-11

NCBI Gene:653240 KRTAP4-11

UCSC:Q9BYQ6 KRTAP4-11

Reference Transcript

RefSeq:NM_033059.3 KRTAP4-11

Other Identifiers

11745692_x_at

16844600

234633_PM_at

234633_at

3721194

3721202

3721203

3756733

3756734

3756735

3756736

3756737

3756741

3756743

3756744

3756753

3756763

3756774

653240

8007115

8015218

8015221

8015230

8019570

8019699

A_23_P4400

GO:0005515

GO:0005829

GO:0005882

GO:0045095

HMNXSV003029403

Hs.307015.0.S1_3p_s_at

Hs.307015.0.S1_3p_x_at

ILMN_1665147

ILMN_2079059

PH_hs_0032602

TC17001489.hg

Participates

as a member of

KRTAP4s [cytosol] (Homo sapiens)

Inferred To

Homologues of KRTAP4-11 [cytosol] (Bos taurus)

KRTAP4-7 [cytosol] (Bos taurus)

Krtap4-9 [cytosol] (Mus musculus)

KRTAP4-11 [cytosol] (Bos taurus)

KRTAP4-11 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENST00000709602, ENSP00000375232, ENST00000573418, ENSP00000517789, ENSP00000460506, ENST00000391413

OpenTargets

ENSG00000212721

HPA

ENSG00000212721-KRTAP4-11

PRO

Q9BYQ6

Pharos - Targets

Q9BYQ6

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.781	11
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.718	8
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.556	3
UniProt:P01137 TGFB1	7	TGFB1 [extracellular region] (R-HSA-170838) TGFB1(30-278) [extracellular region] (R-HSA-2395367) TGFB1(30-278) [Golgi lumen] (R-HSA-9736812) TGFB1 [Golgi lumen] (R-HSA-177108) TGFB1(30-390) [Golgi lumen] (R-HSA-114705) TGFB1 [plasma membrane] (R-HSA-5146781) TGFB1(30-278) [platelet alpha granule lumen] (R-HSA-65936)	0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:O43597 SPRY2	8	p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) SPRY2 [cytosol] (R-HSA-182949) SPRY2 [plasma membrane] (R-HSA-182924) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-Y55-SPRY2 [cytosol] (R-HSA-182950)	0.556	3
UniProt:Q92570 NR4A3	1	NR4A3 [nucleoplasm] (R-HSA-8938004)	0.556	3
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:P07237 P4HB	3	P4HB [endoplasmic reticulum lumen] (R-HSA-174692) p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.556	3
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2

Cite Us!