Reactome | FUCA2 [extracellular region]

FUCA2 [extracellular region]

Stable Identifier

R-HSA-6806227

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Plasma alpha-L-fucosidase ecNumber3.2.1.51/ecNumber, FUCO2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BTY2 FUCA2

Gene Names

FUCA2, PSEC0151, UNQ227/PRO260

Chain

signal peptide:1-28, chain:29-467

Reference Genes

BioGPS Gene:2519 FUCA2

COSMIC (genes):FUCA2 FUCA2

CTD Gene:2519 FUCA2

dbSNP Gene:2519 FUCA2

ENSEMBL:ENSG00000001036 FUCA2

HGNC:4008 FUCA2

KEGG Gene (Homo sapiens):2519 FUCA2

Monarch:2519 FUCA2

NCBI Gene:2519 FUCA2

OMIM:136820 FUCA2

UCSC:Q9BTY2 FUCA2

Reference Transcript

RefSeq:NM_032020.4 FUCA2

Other Identifiers

0005890041

11717740_a_at

11717741_x_at

11758787_at

17024374

223120_at

2519

2977519

2977520

2977521

2977522

2977523

2977526

2977527

2977528

2977529

2977532

2977533

2977536

2977537

2977538

2977539

48543_at

8129974

A_23_P145408

A_33_P3272580

GE56083

GO:0002376

GO:0003674

GO:0004560

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005773

GO:0005783

GO:0005788

GO:0005975

GO:0006004

GO:0006464

GO:0006810

GO:0008150

GO:0008152

GO:0009056

GO:0009617

GO:0016139

GO:0016192

GO:0016787

GO:0016798

GO:0031410

GO:0035578

GO:0043226

GO:0043312

GO:0043687

GO:0044267

GO:0044281

GO:0044403

GO:0070062

GO:2000535

HMNXSV003007260

ILMN_1744914

ILMN_2085362

PH_hs_0028786

TC06002187.hg

g13111747_3p_at

Participates

as a member of

Azurophil granule lumen proteins [extracellular region] (Homo sapiens)

Other forms of this molecule

FUCA2 [azurophil granule lumen]

p-FUCA2 [endoplasmic reticulum lumen]

FUCA2 [endoplasmic reticulum lumen]

Inferred To

fuca2 [extracellular region] (Danio rerio)

Fuca [extracellular region] (Drosophila melanogaster)

Fuca2 [extracellular region] (Mus musculus)

Fuca2 [extracellular region] (Rattus norvegicus)

alfA [extracellular region] (Dictyostelium discoideum)

FUCA2 [extracellular region] (Bos taurus)

FUCA2 [extracellular region] (Caenorhabditis elegans)

FUCA2 [extracellular region] (Canis familiaris)

FUCA2 [extracellular region] (Dictyostelium discoideum)

FUCA2 [extracellular region] (Gallus gallus)

FUCA2 [extracellular region] (Sus scrofa)

Homologues of FUCA2 [extracellular region] (Dictyostelium discoideum)

Cross References

RefSeq

NP_114409.2

OpenTargets

ENSG00000001036

IntEnz

3.2.1.51

HPA

ENSG00000001036-FUCA2

ZINC - Substances

FUCO2_HUMAN

GeneCards

Q9BTY2

Ensembl

ENSG00000001036, ENSP00000002165, ENST00000002165

ZINC target

Q9BTY2

PRO

Q9BTY2

ZINC - Predictions - Purchasable

FUCO2_HUMAN

HMDB Protein

HMDBP00876

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3