In epithelial cells, FGFR2 IIIb-specific alternative splicing is favoured by the binding of ESRP1 and 2, RBFOX2, TIA1 and TIAL1 to the nascent transcript. These proteins, in conjunction with other splicing factors, activate exon IIIb-specific splicing and repress exon IIIc-specific splicing (Warzecha et al, 2009; Baraniak et al, 2006; Mauger et al, 2008; Hovhannisyan and Carstens, 2007; Del Gatto et al, 2000).
Baraniak, AP, Chen, JR, Garcia-Blanco, MA
Mauger, DM, Lin, C, Garcia-Blanco, MA
Hovhannisyan, RH, Carstens, RP
Del Gatto-Konczak, F, Bourgeois, CF, Le Guiner, C, Kister, L, Gesnel, MC, Stévenin, J, Breathnach, R
Warzecha, CC, Sato, TK, Nabet, B, Hogenesch, JB, Carstens, RP
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