PLK2 phosphorylates CENPJ

Stable Identifier
R-HSA-6801666
Type
Reaction
Species
Homo sapiens
Compartment
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PLK2 phosphorylates centrosome protein CENPJ (CPAP) on serine residues S589 and S585, which is a prerequisite for procentriole formation and centrosome duplication (Chang et al. 2010).

Literature References
PubMed ID Title Journal Year
20531387 PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle

Rhee, K, Chang, J, Hoffmann, I, Cizmecioglu, O

EMBO J. 2010
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of PLK2 [cytosol]

Orthologous Events
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