Reactome | FGL2 [extracellular region]

FGL2 [extracellular region]

Stable Identifier

R-HSA-6801586

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Fibroleukin, FGL2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14314 FGL2

Gene Names

FGL2

Chain

signal peptide:1-23, chain:24-439

Reference Genes

BioGPS Gene:10875 FGL2

COSMIC (genes):FGL2 FGL2

CTD Gene:10875 FGL2

dbSNP Gene:10875 FGL2

ENSEMBL:ENSG00000127951 FGL2

ENSEMBL_homo_sapiens_GENE:ENSG00000127951.8 FGL2

HGNC:3696 FGL2

KEGG Gene (Homo sapiens):10875 FGL2

Monarch:10875 FGL2

NCBI Gene:10875 FGL2

OMIM:605351 FGL2

UCSC:Q14314 FGL2

Reference Transcript

RefSeq:NM_006682.2 FGL2

Other Identifiers

10875

11722426_a_at

11722427_at

11758630_s_at

17058968

204834_PM_at

204834_at

227265_PM_at

227265_at

3057956

3057957

3057958

3057959

3057960

3057961

3057962

3057963

3057964

3057965

3057966

3057967

3057968

3057969

3057970

39591_s_at

39592_r_at

39593_at

62189_at

8140463

A_23_P42969

A_33_P3332018

GE60401

GE86053

GO:0002291

GO:0002376

GO:0002605

GO:0002617

GO:0005198

GO:0005201

GO:0005515

GO:0005576

GO:0005577

GO:0005615

GO:0007155

GO:0030154

GO:0030312

GO:0031012

GO:0031410

GO:0043226

GO:0043381

GO:0048856

GO:0050687

GO:0062023

GO:0070062

GO:0098542

GO:1904813

HMNXSV003040584

Hs.296276.0.A1_3p_at

ILMN_1693009

PH_hs_0017012

PH_hs_0030775

TC07001546.hg

TC07003035.hg

Z36531_at

g5730074_3p_at

Participates

as a member of

Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)

Other forms of this molecule

FGL2 [ficolin-1-rich granule lumen]

Inferred To

Fgl2 [extracellular region] (Mus musculus)

Fgl2 [extracellular region] (Rattus norvegicus)

FGL2 [extracellular region] (Bos taurus)

FGL2 [extracellular region] (Canis familiaris)

FGL2 [extracellular region] (Gallus gallus)

FGL2 [extracellular region] (Sus scrofa)

fgl2a [extracellular region] (Danio rerio)

Cross References

RefSeq

NP_006673.1

OpenTargets

ENSG00000127951

GeneCards

Q14314

HPA

ENSG00000127951-FGL2

Ensembl

ENST00000248598, ENSP00000248598, ENSG00000127951

PRO

Q14314

Pharos - Targets

Q14314

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UM82 SPATA2	1	SPATA2 [cytosol] (R-HSA-9796351)	0.527	2
UniProt:Q2M1P5 KIF7	1	KIF7 [ciliary tip] (R-HSA-5610395)	0.527	2
UniProt:Q9BYC5 FUT8	1	FUT8 [Golgi membrane] (R-HSA-1028782)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.508	6

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