Reactome | ACPP [azurophil granule membrane]

ACPP [azurophil granule membrane]

Stable Identifier

R-HSA-6799214

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule membrane

Synonyms

Prostatic acid phosphatase, PPAP_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P15309 ACP3

Gene Names

ACP3, ACPP

Chain

signal peptide:1-32, chain:33-386, peptide:248-286

Reference Genes

BioGPS Gene:55 ACP3

CTD Gene:55 ACP3

dbSNP Gene:55 ACP3

ENSEMBL:ENSG00000014257 ACPP

ENSEMBL_homo_sapiens_GENE:ENSG00000014257.17 ACP3

HGNC:125 ACP3

KEGG Gene (Homo sapiens):55 ACP3

Monarch:55 ACP3

NCBI Gene:55 ACP3

OMIM:171790 ACP3

UCSC:P15309 ACP3

Reference Transcript

Other Identifiers

11729013_at

11739048_at

11739049_at

11739050_s_at

11748861_a_at

16945682

204393_PM_s_at

204393_s_at

237030_PM_at

237030_at

2642729

2642730

2642731

2642734

2642736

2642737

2642742

2642743

2642749

2642752

2642754

2642755

2642757

2642758

2642759

2642760

2642761

2642762

2642763

2642765

2642766

2642767

32200_at

617_at

8082673

80874_at

A_14_P101781

A_24_P46130

GE79467

GO:0003824

GO:0003993

GO:0004725

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005771

GO:0005773

GO:0005794

GO:0005829

GO:0005886

GO:0006144

GO:0006629

GO:0006766

GO:0006772

GO:0006790

GO:0007040

GO:0008253

GO:0009117

GO:0012506

GO:0016020

GO:0016311

GO:0016787

GO:0016791

GO:0023052

GO:0030141

GO:0030175

GO:0031410

GO:0031985

GO:0033265

GO:0035577

GO:0042131

GO:0042802

GO:0042803

GO:0043226

GO:0045177

GO:0046085

GO:0050877

GO:0051930

GO:0052642

GO:0055086

GO:0060090

GO:0060168

GO:0070062

GO:0106411

GO:0140096

GO:1901135

HMNXSV003019762

HMNXSV003030812

Hs.152298.0.A1_3p_at

ILMN_1758323

M24902_at

PH_hs_0024475

TC03000714.hg

g6382063_3p_at

Participates

as a member of

Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)

Other forms of this molecule

ACPP [plasma membrane]

Inferred To

ACP3 [azurophil granule membrane] (Canis familiaris)

ACP3 [azurophil granule membrane] (Sus scrofa)

acp-5 [azurophil granule membrane] (Caenorhabditis elegans)

pho-14 [azurophil granule membrane] (Caenorhabditis elegans)

pho-1 [azurophil granule membrane] (Caenorhabditis elegans)

pho-6 [azurophil granule membrane] (Caenorhabditis elegans)

pho-10 [azurophil granule membrane] (Caenorhabditis elegans)

acp-6 [azurophil granule membrane] (Caenorhabditis elegans)

cf60 [azurophil granule membrane] (Dictyostelium discoideum)

Acph-1 [azurophil granule membrane] (Drosophila melanogaster)

Dmel\CG9452 [azurophil granule membrane] (Drosophila melanogaster)

Homologues of ACPP [azurophil granule membrane] (Caenorhabditis elegans)

Homologues of ACPP [azurophil granule membrane] (Dictyostelium discoideum)

Homologues of ACPP [azurophil granule membrane] (Drosophila melanogaster)

Homologues of ACPP [azurophil granule membrane] (Xenopus tropicalis)

pho-5 [azurophil granule membrane] (Caenorhabditis elegans)

Dmel\CG6656 [azurophil granule membrane] (Drosophila melanogaster)

acp-7 [azurophil granule membrane] (Caenorhabditis elegans)

acp3 [azurophil granule membrane] (Xenopus tropicalis)

pho-11 [azurophil granule membrane] (Caenorhabditis elegans)

pho-4 [azurophil granule membrane] (Caenorhabditis elegans)

acp2 [azurophil granule membrane] (Danio rerio)

acp2 [azurophil granule membrane] (Xenopus tropicalis)

pho-9 [azurophil granule membrane] (Caenorhabditis elegans)

Dmel\CG9451 [azurophil granule membrane] (Drosophila melanogaster)

Dmel\CG9449 [azurophil granule membrane] (Drosophila melanogaster)

pho-12 [azurophil granule membrane] (Caenorhabditis elegans)

ACPP [azurophil granule membrane] (Bos taurus)

ACPP [azurophil granule membrane] (Caenorhabditis elegans)

ACPP [azurophil granule membrane] (Dictyostelium discoideum)

ACPP [azurophil granule membrane] (Gallus gallus)

ACPP [azurophil granule membrane] (Mus musculus)

ACPP [azurophil granule membrane] (Rattus norvegicus)

ACPP [azurophil granule membrane] (Schizosaccharomyces pombe)

pho-7 [azurophil granule membrane] (Caenorhabditis elegans)

pho-8 [azurophil granule membrane] (Caenorhabditis elegans)

pho-13 [azurophil granule membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001278966.1, NP_001090.2, NP_001127666.1

OpenTargets

ENSG00000014257

ZINC - Substances

PPAP_HUMAN

ZINC target

P15309

PRO

P15309

PDB

1CVI, 1ND6, 2L77, 2MG0, 7ZZV, 2L3H, 2L79, 2HPA, 8XJ4, 3PPD, 1ND5

IntEnz

3.1.3.48

GeneCards

P15309

HPA

ENSG00000014257-ACP3

Ensembl

ENST00000351273, ENST00000475741, ENSG00000014257, ENSP00000337471, ENSP00000417744, ENST00000336375, ENSP00000323036

Pharos - Targets

P15309

ZINC - Predictions - Purchasable

PPAP_HUMAN

HMDB Protein

HMDBP00098

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04626 ERBB2	20	ERBB2 G309E [plasma membrane] (R-HSA-9665342) ERBB2 G309A [plasma membrane] (R-HSA-9665349) ERBB2 S310F [plasma membrane] (R-HSA-9665350) ERBB2 S310Y [plasma membrane] (R-HSA-9665344) p-6Y-ERBB2 G309A [plasma membrane] (R-HSA-9665381) p-6Y-ERBB2 G309E [plasma membrane] (R-HSA-9665382) p-6Y-ERBB2 S310F [plasma membrane] (R-HSA-9665379) p-6Y-ERBB2 S310Y [plasma membrane] (R-HSA-9665385) p-Y-ERBB2 L755P [plasma membrane] (R-HSA-9654268) p-Y-ERBB2 I767M [plasma membrane] (R-HSA-9654303) p-Y-ERBB2 T798I [plasma membrane] (R-HSA-9654618) p-Y-ERBB2 Y772_A775dup [plasma membrane] (R-HSA-9665652) p-Y-ERBB2 T862A [plasma membrane] (R-HSA-9654695) p-Y-ERBB2 T798M [plasma membrane] (R-HSA-9654615) p-Y-ERBB2 H878Y [plasma membrane] (R-HSA-9654833) p-Y-ERBB2 V777L [plasma membrane] (R-HSA-9654401) p-Y-ERBB2 L755S [plasma membrane] (R-HSA-9654194) p-Y-ERBB2 V777E [plasma membrane] (R-HSA-9654397) p-Y-ERBB2 V777M [plasma membrane] (R-HSA-9654398) p-Y-ERBB2 L755M [plasma membrane] (R-HSA-9654191)	0.472	2

Cite Us!