Reactome | ASPG [cytosol]

ASPG [cytosol]

Stable Identifier

R-HSA-6797634

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

60 kDa lysophospholipase ecNumber3.1.1.5/ecNumber domain recommendedName: L-asparaginase ecNumber3.5.1.1/ecNumber, LPP60_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q86U10 ASPG

Gene Names

ASPG, C14orf76

Chain

chain:1-573

Reference Genes

BioGPS Gene:374569 ASPG

COSMIC (genes):ASPG ASPG

CTD Gene:374569 ASPG

dbSNP Gene:374569 ASPG

ENSEMBL:ENSG00000166183.16 ASPG

HGNC:20123 ASPG

KEGG Gene (Homo sapiens):374569 ASPG

Monarch:374569 ASPG

NCBI Gene:374569 ASPG

OMIM:618472 ASPG

UCSC:Q86U10 ASPG

Reference Transcript

Other Identifiers

11740551_a_at

11740552_at

1557225_PM_at

1557225_at

1557226_PM_a_at

1557226_a_at

16789377

16789400

3554063

3554064

3554065

3554068

3554069

3554070

3554071

3554072

3554074

3554075

3554079

3554080

3554081

3554082

3554083

3554085

3554086

3554089

3554090

3554091

3554092

3554093

3554094

3554095

3554096

3554097

374569

7977203

7977214

90122_f_at

90124_r_at

A_23_P76743

GE748097

GE88152

GO:0003824

GO:0003847

GO:0004067

GO:0004622

GO:0005515

GO:0005829

GO:0006520

GO:0006629

GO:0009066

GO:0016042

GO:0016740

GO:0016746

GO:0016747

GO:0016787

GO:0102545

HMNXSV003039423

HMNXSV003054777

Hs2.146239.1.S1_3p_s_at

PH_hs_0008723

TC14000811.hg

TC14000812.hg

Inferred To

ASPG [cytosol] (Bos taurus)

ASPG [cytosol] (Caenorhabditis elegans)

ASPG [cytosol] (Canis familiaris)

ASPG [cytosol] (Danio rerio)

ASPG [cytosol] (Drosophila melanogaster)

ASPG [cytosol] (Gallus gallus)

ASPG [cytosol] (Mus musculus)

ASPG [cytosol] (Rattus norvegicus)

ASPG [cytosol] (Sus scrofa)

ASPG [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001073933.2, XP_005267647.1

Guide to Pharmacology - Targets

2762

OpenTargets

ENSG00000166183

IntEnz

3.1.1.47

GeneCards

Q86U10

HPA

ENSG00000166183-ASPG

Ensembl

ENSG00000166183, ENST00000551177, ENSP00000450040

PRO

Q86U10

Pharos - Targets

Q86U10

HMDB Protein

HMDBP07300

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.556	3
UniProt:P40199 CEACAM6	2	GPI-CEACAM6 [azurophil granule membrane] (R-HSA-6799133) GPI-CEACAM6 [plasma membrane] (R-HSA-204085)	0.556	3
UniProt:Q9BXF9 TEKT3			0.556	3
UniProt:Q9BRG1 VPS25	1	VPS25 [cytosol] (R-HSA-917697)	0.556	5
UniProt:Q14D33 RTP5			0.556	3
UniProt:Q8TDC0 MYOZ3			0.556	3
UniProt:Q9H1P6 CT085			0.556	3
UniProt:Q92529 SHC3	2	SHC3 [cytosol] (R-HSA-3006448) p-Y-SHC3 [cytosol] (R-HSA-3009043)	0.556	3
UniProt:P57764 GSDMD	13	GSDMD [specific granule lumen] (R-HSA-6801468) GSDMD [tertiary granule lumen] (R-HSA-6801501) GSDMD [extracellular region] (R-HSA-6801576) GSDMD [ficolin-1-rich granule lumen] (R-HSA-6801498) GSDMD(88-484) [cytosol] (R-HSA-9686133) GSDMD(1-87) [cytosol] (R-HSA-9686099) GSDMD(1-275) [cytosol] (R-HSA-9647641) GSDMD [cytosol] (R-HSA-6801577) GSDMD(276-484) [cytosol] (R-HSA-9647672) S-(2-succinyl)-C191-GSDMD [cytosol] (R-HSA-9716198) GSDMD(269-484) [cytosol] (R-HSA-9710116) GSDMD(1-268) [cytosol] (R-HSA-9710104) dithiocarb-C191-GSDMD(1-275) [cytosol] (R-HSA-9693317)	0.556	3
UniProt:Q12893 TMEM115	1	TMEM115 [Golgi membrane] (R-HSA-6808815)	0.556	3

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