28S rRNA:12S pre-rRNA:Rix1:LAS1L:NOL9:SENP3:PeBoW [nucleoplasm]

Stable Identifier
R-HSA-6791568
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
17353269 Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit

Gruber-Eber, A, Harasim, T, Grimm, T, Malamoussi, A, Eick, D, Orban, M, Rohrmoser, M, Kremmer, E, Pfisterer, I, Hölzel, M

Mol. Cell. Biol. 2007
16738141 Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex

Gruber-Eber, A, Harasim, T, Grimm, T, Malamoussi, A, Eick, D, Rohrmoser, M, Kremmer, E, Hölzel, M

Nucleic Acids Res. 2006
16043514 Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

Gruber-Eber, A, Schlee, M, Harasim, T, Grimm, T, Malamoussi, A, Eick, D, Bornkamm, GW, Rohrmoser, M, Hiddemann, W, Kremmer, E, Hölzel, M

J. Cell Biol. 2005
17189298 The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing

Gruber-Eber, A, Harasim, T, Grimm, T, Malamoussi, A, Eick, D, Rohrmoser, M, Kremmer, E, Hölzel, M

Nucleic Acids Res. 2007
22190735 LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis

Denicourt, C, Cassimere, EK, Castle, CD

Mol. Biol. Cell 2012
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