TP53 stimulates BCL2L14 gene expression

Stable Identifier
Reaction [omitted]
Homo sapiens
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Binding of TP53 (p53) to p53 response element(s) in the first intron and, possibly, the promoter region of BCL2L14 stimulates transcription of the BCL2L14 gene. BCL2L14 (BCLG) is a BCL2 family member with an unknown function and a proposed but uncertain pro-apoptotic role (Guo et al. 2001, Giam et al. 2012).

Literature References
PubMed ID Title Journal Year
15958553 A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network

Garbay, S, Miled, C, Weitzman, JB, Yaniv, M, Pontoglio, M

Cancer Res. 2005
23059823 Bcl-2 family member Bcl-G is not a proapoptotic protein

Bouillet, P, Giam, M, Strasser, A, Mintern, JD, Okamoto, T

Cell Death Dis 2012
11054413 Bcl-G, a novel pro-apoptotic member of the Bcl-2 family

Godzik, A, Reed, JC, Guo, B

J. Biol. Chem. 2001
This event is regulated