Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Author/Reviewer Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Author/Reviewer Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
Search ...
Go!
GADD45A:AURKA
Stable Identifier
R-HSA-6791236
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Homo sapiens)
GADD45A binds AURKA (Homo sapiens)
GADD45A:AURKA [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
16772293
Gadd45a interacts with aurora-A and inhibits its kinase activity
J. Biol. Chem.
2006
20460379
Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase
J. Biol. Chem.
2010
Participants
components
AURKA [nucleoplasm] (Homo sapiens)
GADD45A [nucleoplasm] (Homo sapiens)
Participant Of
output
GADD45A binds AURKA
Inferred To
GADD45A:AURKA [nucleoplasm] (Bos taurus)
GADD45A:AURKA [nucleoplasm] (Canis familiaris)
GADD45A:AURKA [nucleoplasm] (Danio rerio)
GADD45A:AURKA [nucleoplasm] (Gallus gallus)
GADD45A:AURKA [nucleoplasm] (Mus musculus)
GADD45A:AURKA [nucleoplasm] (Rattus norvegicus)
GADD45A:AURKA [nucleoplasm] (Sus scrofa)
GADD45A:AURKA [nucleoplasm] (Xenopus tropicalis)
© 2018
Reactome
