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Ub-HIST1H2BL [nucleoplasm]
Stable Identifier
R-HSA-6782543
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST1H2BL, Histone H2B.c
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BL [nucleoplasm] (Homo sapiens)
USP49 deubiquitinates H2B (Homo sapiens)
USP49:Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BL [nucleoplasm] (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
RNF20:RNF40 monoubiquitinates Histone H2B (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BL [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99880 H2BC13
Gene Names
H2BC13, H2BFC, HIST1H2BL
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:8340 H2BC13
CTD Gene:8340 H2BC13
dbSNP Gene:8340 H2BC13
ENSEMBL:ENSG00000185130 HIST1H2BL
ENSEMBL_homo_sapiens_GENE:ENSG00000185130.6 H2BC13
HGNC:4748 H2BC13
KEGG Gene (Homo sapiens):8340 H2BC13
Monarch:8340 H2BC13
NCBI Gene:8340 H2BC13
OMIM:602800 H2BC13
UCSC:Q99880 H2BC13
Reference Transcript
RefSeq:NM_003519.3 H2BC13
Other Identifiers
11740828_at
17016486
207611_PM_at
2947033
2947034
2947035
35576_f_at
36347_f_at
8124510
8340
ADDON002867.hg
A_23_P8013
GE511997
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0065003
GO:0070062
HMNXSV003013302
ILMN_1652998
PH_hs_0029201
PH_hs_0031779
TC06001421.hg
g5579460_3p_at
Participates
as a member of
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Other forms of this molecule
AcK-HIST1H2BL [nucleoplasm]
HIST1H2BL [extracellular region]
AcK13-HIST1H2BL [nucleoplasm]
AcK16-HIST1H2BL [nucleoplasm]
AcK6-HIST1H2BL [nucleoplasm]
AcK21-HIST1H2BL [nucleoplasm]
Ub-121-HIST1H2BL [nucleoplasm]
HIST1H2BL [nucleoplasm]
Inferred To
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of Ub-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
Hist1h2bp [nucleoplasm]
(Mus musculus)
Homologues of Ub-HIST1H2BL [nucleoplasm]
(Mus musculus)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
Ub-HIST1H2BC [nucleoplasm]
(Danio rerio)
H2B-V [nucleoplasm]
(Gallus gallus)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
H2B-I [nucleoplasm]
(Gallus gallus)
H2bc3 [nucleoplasm]
(Mus musculus)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
Hist1h2bc [nucleoplasm]
(Rattus norvegicus)
H2bc7 [nucleoplasm]
(Mus musculus)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
si:ch211-113a14.29 [nucleoplasm]
(Danio rerio)
Ub-HIST1H2BL [nucleoplasm]
(Bos taurus)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
H1-2 [nucleoplasm]
(Sus scrofa)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine (monoUb [nucleoplasm]) at 120
Coordinate
120
Modification
monoUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_003510.1
OpenTargets
ENSG00000185130
HPA
ENSG00000185130-H2BC13
GeneCards
Q99880
Ensembl
ENST00000377401
,
ENSP00000366618
,
ENSG00000185130
PRO
Q99880
Pharos - Targets
Q99880
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.556
3
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