Highly calcium permeable nicotinic acetylcholine receptors

Stable Identifier
R-HSA-629597
Type
Pathway
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
ReviewStatus
5/5
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Highly calcium permeable nicotinic acetylcholine receptors
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Nicotinic acetylcholine receptors exhibit high influx of Ca2+, the degree of Ca2+ permeability is dependent on the subunit composition; homomeric acetylcholine receptors containing aplha 7 subunits allow maximum Ca2+ influx followed by receptors containing alpha3 beta2 alpha5 or alpha3 beta4 alpha5.

Literature References
PubMed ID Title Journal Year
14670366 Ca2+ permeability of nicotinic acetylcholine receptors

Fucile, S

Cell Calcium 2004
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
chemical synaptic transmission (0007268)
Orthologous Events
Highly calcium permeable nicotinic acetylcholine receptors (Bos taurus)
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Highly calcium permeable nicotinic acetylcholine receptors (Canis familiaris)
Highly calcium permeable nicotinic acetylcholine receptors (Danio rerio)
Highly calcium permeable nicotinic acetylcholine receptors (Drosophila melanogaster)
Highly calcium permeable nicotinic acetylcholine receptors (Gallus gallus)
Highly calcium permeable nicotinic acetylcholine receptors (Mus musculus)
Highly calcium permeable nicotinic acetylcholine receptors (Rattus norvegicus)
Highly calcium permeable nicotinic acetylcholine receptors (Sus scrofa)
Highly calcium permeable nicotinic acetylcholine receptors (Xenopus tropicalis)
Authored
Mahajan, SS  (2010-04-22)
Reviewed
Restituito, S  (2008-11-27)
Wen, H  (2020-01-24)
Created
Mahajan, SS  (2010-04-27)
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