Highly sodium permeable postsynaptic acetylcholine nicotinic receptors

Stable Identifier
R-HSA-629587
Type
Pathway
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
ReviewStatus
5/5
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Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
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Nicotinic acetylcholne receptors that have low Ca2+ permeability allow the influx of Na+ which causes depolarization of the membrane initiating voltage dependent responses such as activation of voltage dependent opening of Ca2+ channels and thus eliciting an increase in Ca2+ and downstream signaling. These receptors could be found in both presynaptic and postsynaptic terminals.
Literature References
PubMed ID Title Journal Year
9110108 Nicotine and sympathetic neurotransmission

Kübler, W, Haass, M

Cardiovasc Drugs Ther 1997
Participants
Events
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as an event of
Event Information
Go Biological Process
chemical synaptic transmission (0007268)
Orthologous Events
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Bos taurus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Caenorhabditis elegans)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Canis familiaris)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Drosophila melanogaster)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Gallus gallus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Mus musculus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Rattus norvegicus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Xenopus tropicalis)
Authored
Mahajan, SS  (2010-04-27)
Reviewed
Restituito, S  (2008-11-27)
Wen, H  (2020-01-24)
Created
Mahajan, SS  (2010-04-27)
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