Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors

Stable Identifier
R-HSA-622325
Type
Reaction
Species
Homo sapiens
Compartment
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Nicotinic acetylcholine receptors containing aplha4(2) beta2 (3) and alpha3(2) beta4(3) are selectively highly Na+ permeable upon activation of these receptors by acetylcholine.

Literature References
PubMed ID Title Journal Year
8987816 Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study

Sullivan, JP, Buisson, B, Bertrand, D, Gopalakrishnan, M, Arneric, SP

J Neurosci 1996
Participants
Output
Participates
Catalyst Activity

ligand-gated ion channel activity of O-Acetylcholine bound to Acetylcholine receptor [plasma membrane]

Orthologous Events
Cross References
Rhea
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