CCAN:DNA:CASC5 [nucleoplasm]

Stable Identifier
R-HSA-606340
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
Constitutive centromere-associated network:DNA:CASC5
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General

The mechanism of interaction between the CENPH-I Complex and the centromeric nucleosome (containing CENPA) is unknown. The CENH-I complex is observed to interact with the centromeric core throughout the cell cycle.

Literature References
PubMed ID Title Journal Year
19543270 Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N

Jansen, LE, Straight, AF, Godek, KM, Silva, MC, Carroll, CW

Nat Cell Biol 2009
15009096 Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase

Okazaki, T, Goto, S, Yoda, K, Obuse, C, Nozaki, N, Yang, H

Genes Cells 2004
16622419 The human CENP-A centromeric nucleosome-associated complex

Jansen, LE, Yates, JR 3rd, Foltz, DR, Black, BE, Bailey, AO, Cleveland, DW

Nat Cell Biol 2006
16622420 The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres

Okada, M, McLeod, IX, Hori, T, Yates, JR 3rd, Cheeseman, IM, Okawa, K, Fukagawa, T, Desai, A

Nat Cell Biol 2006
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