CCAN:DNA:CASC5

Stable Identifier
R-HSA-606340
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Constitutive centromere-associated network:DNA:CASC5
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Summation

The mechanism of interaction between the CENPH-I Complex and the centromeric nucleosome (containing CENPA) is unknown. The CENH-I complex is observed to interact with the centromeric core throughout the cell cycle.

Literature References
PubMed ID Title Journal Year
16622420 The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres

Okada, M, Cheeseman, IM, Hori, T, Okawa, K, McLeod, IX, Yates, JR 3rd, Desai, A, Fukagawa, T

Nat Cell Biol 2006
19543270 Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N

Carroll, CW, Silva, MC, Godek, KM, Jansen, LE, Straight, AF

Nat Cell Biol 2009
15009096 Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase

Obuse, C, Yang, H, Nozaki, N, Goto, S, Okazaki, T, Yoda, K

Genes Cells 2004
16622419 The human CENP-A centromeric nucleosome-associated complex

Foltz, DR, Jansen, LE, Black, BE, Bailey, AO, Yates, JR 3rd, Cleveland, DW

Nat Cell Biol 2006
Participants
components
Participant Of
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Inferred To
CCAN:DNA:CASC5 [nucleoplasm] (Bos taurus)
CCAN:DNA:CASC5 [nucleoplasm] (Canis familiaris)
CCAN:DNA:CASC5 [nucleoplasm] (Danio rerio)
CCAN:DNA:CASC5 [nucleoplasm] (Gallus gallus)
CCAN:DNA:CASC5 [nucleoplasm] (Mus musculus)
CCAN:DNA:CASC5 [nucleoplasm] (Rattus norvegicus)
CCAN:DNA:CASC5 [nucleoplasm] (Sus scrofa)
CCAN:DNA:CASC5 [nucleoplasm] (Taeniopygia guttata)