Reactome | ETV4 [nucleoplasm]

ETV4 [nucleoplasm]

Stable Identifier

R-HSA-5687030

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PEA3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P43268 ETV4

Gene Names

ETV4, E1AF, PEA3

Chain

chain:1-484

Reference Genes

BioGPS Gene:2118 ETV4

COSMIC - genes:ETV4 ETV4

CTD Gene:2118 ETV4

dbSNP Gene:2118 ETV4

ENSEMBL:ENSG00000175832 ETV4

HGNC:3493 ETV4

KEGG:hsa:2118 ETV4

Monarch:2118 ETV4

NCBI Gene:2118 ETV4

OMIM:600711 ETV4

UCSC:P43268 ETV4

Reference Transcript

Participates

as an input of

p-S857 NCOA3 binds ETV4 (Homo sapiens)

as a component of

p-S857 NCOA3:ETV4 [nucleoplasm] (Homo sapiens)

Inferred To

Homologues of ETV4 [nucleoplasm] (Caenorhabditis elegans)

ets-9 [nucleoplasm] (Caenorhabditis elegans)

ETV4 [nucleoplasm] (Bos taurus)

ETV4 [nucleoplasm] (Caenorhabditis elegans)

ETV4 [nucleoplasm] (Canis familiaris)

ETV4 [nucleoplasm] (Gallus gallus)

ETV4 [nucleoplasm] (Sus scrofa)

ets-8 [nucleoplasm] (Caenorhabditis elegans)

etv4 [nucleoplasm] (Danio rerio)

etv4 [nucleoplasm] (Xenopus tropicalis)

Ets96B [nucleoplasm] (Drosophila melanogaster)

Etv4 [nucleoplasm] (Mus musculus)

Etv4 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001248367.1, NP_001248366.1, NP_001248368.1, NP_001977.1, NP_001073143.1, XP_047291549.1, NP_001356295.1

OpenTargets

ENSG00000175832

ENSEMBL

ENSP00000440023, ENSP00000377273, ENSP00000443846, ENSP00000468636, ENSG00000175832, ENST00000545954, ENST00000586826, ENST00000393664, ENSP00000465718, ENSP00000321835, ENST00000591713, ENST00000538265, ENST00000319349

HPA

ENSG00000175832-ETV4

GeneCards

ETV4

PRO

P43268

Pharos - Targets

P43268

Orphanet

ETV4

PDB

5ILU, 4CO8, 4UUV

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.625	6
UniProt:P14079 TAX			0.556	3

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