CHEK1 phosphorylates RAD51

Stable Identifier
R-HSA-5685230
Type
Reaction
Species
Homo sapiens
Compartment
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Activated CHEK1 phosphorylates RAD51 on threonine residue T309, which is necessary for RAD51 association with chromatin (Sorensen et al. 2005).

Literature References
PubMed ID Title Journal Year
15665856 The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Lundin, C, Bartek, J, Dziegielewski, J, Helleday, T, Hansen, LT, Sørensen, CS, Syljuåsen, RG

Nat. Cell Biol. 2005
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]

Orthologous Events
Authored
Reviewed
Created
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