Reactome | p-EYA3 [nucleoplasm]

p-EYA3 [nucleoplasm]

Stable Identifier

R-HSA-5683979

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99504 EYA3

Gene Names

EYA3

Chain

chain:1-573

Reference Genes

BioGPS Gene:2140 EYA3

COSMIC (genes):EYA3 EYA3

CTD Gene:2140 EYA3

dbSNP Gene:2140 EYA3

ENSEMBL:ENSG00000158161 EYA3

ENSEMBL_homo_sapiens_GENE:ENSG00000158161.16 EYA3

HGNC:3521 EYA3

KEGG Gene (Homo sapiens):2140 EYA3

Monarch:2140 EYA3

NCBI Gene:2140 EYA3

OMIM:601655 EYA3

UCSC:Q99504 EYA3

Reference Transcript

Other Identifiers

11743304_a_at

11745458_a_at

11746219_a_at

11749047_x_at

11759488_at

1552314_PM_a_at

1552314_a_at

1554844_PM_at

1554844_at

16684110

206379_PM_at

206379_at

2140

226170_PM_at

226170_at

2403298

2403336

2403337

2403338

2403339

2403340

2403341

2403342

2403345

2403347

2403348

2403349

2403351

2403352

2403354

2403355

2403356

2403357

2403358

2403359

2403361

2403364

2403371

2403372

2403381

2403382

2403383

3036620

36693_at

53802_at

7914153

A_23_P74737

A_24_P122658

A_24_P466374

GE60278

GE850242

GO:0003824

GO:0004721

GO:0004725

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0006281

GO:0006302

GO:0006325

GO:0006338

GO:0006974

GO:0007275

GO:0007601

GO:0009653

GO:0010212

GO:0012501

GO:0016787

GO:0023052

GO:0030154

GO:0043226

GO:0045739

GO:0046872

GO:0048856

GO:0050877

GO:0140096

GO:0140793

GO:2001240

HMNXSV003003226

HMNXSV003007035

HMNXSV003056197

Hs.293850.0.A1_3p_at

Hs2.46925.1.S1_3p_s_at

Hs2.46925.3.S1_3p_at

ILMN_1728353

ILMN_1790562

PH_hs_0024669

TC01002416.hg

Y10262_s_at

g4503620_3p_at

Participates

as a member of

p-EYA1-4 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

EYA3 [nucleoplasm]

Inferred To

phospho-p-EYA3 [nucleoplasm] (Bos taurus)

phospho-p-EYA3 [nucleoplasm] (Caenorhabditis elegans)

phospho-p-EYA3 [nucleoplasm] (Canis familiaris)

phospho-p-EYA3 [nucleoplasm] (Danio rerio)

phospho-p-EYA3 [nucleoplasm] (Drosophila melanogaster)

phospho-p-EYA3 [nucleoplasm] (Gallus gallus)

phospho-p-EYA3 [nucleoplasm] (Mus musculus)

phospho-p-EYA3 [nucleoplasm] (Rattus norvegicus)

phospho-p-EYA3 [nucleoplasm] (Sus scrofa)

phospho-p-EYA3 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_001269489.1, NP_001981.2, NP_001269490.1, NP_001269491.1

OpenTargets

ENSG00000158161

GeneCards

Q99504

HPA

ENSG00000158161-EYA3

Ensembl

ENSG00000158161, ENST00000373871, ENSP00000362978, ENST00000373863, ENST00000540618, ENSP00000362970, ENSP00000405587, ENSP00000442558, ENST00000436342

PRO

Q99504

Pharos - Targets

Q99504

HMDB Protein

HMDBP08722

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:P16284 PECAM1	4	PECAM1 [plasma membrane] (R-HSA-114686) p-Y663,Y686-PECAM1(27-?) [plasma membrane] (R-HSA-210007) PECAM1 [secretory granule membrane] (R-HSA-6804778) PECAM1 [platelet alpha granule membrane] (R-HSA-61489)	0.556	3
UniProt:P10809 HSPD1	6	HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.556	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3