Reactome | SEPT2 [cytosol]

SEPT2 [cytosol]

Stable Identifier

R-HSA-5626657

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser for interactor UniProt:Q14141 SEPT6

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External Reference Information

External Reference

UniProt:Q15019 SEPTIN2

Gene Names

SEPTIN2, DIFF6, KIAA0158, NEDD5, SEPT2

Chain

chain:1-361

Reference Genes

BioGPS Gene:4735 SEPTIN2

COSMIC - genes:SEPT2 SEPTIN2

CTD Gene:4735 SEPTIN2

dbSNP Gene:4735 SEPTIN2

ENSEMBL:ENSG00000168385 SEPTIN2

HGNC:7729 SEPTIN2

KEGG:hsa:4735 SEPTIN2

Monarch:4735 SEPTIN2

NCBI Gene:4735 SEPTIN2

OMIM:601506 SEPTIN2

UCSC:Q15019 SEPTIN2

Reference Transcript

This entity regulates

Positively

Recruitment of transition zone proteins (Homo sapiens)

Inferred To

LOC119868838 [cytosol] (Canis familiaris)

SEPT2 [cytosol] (Bos taurus)

SEPT2 [cytosol] (Mus musculus)

SEPT2 [cytosol] (Rattus norvegicus)

SEPTIN2 [cytosol] (Gallus gallus)

SEPTIN2 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_001336217.1, NP_001336218.1, NP_001336219.1, NP_001307959.1, NP_001307958.1, XP_024308693.1, XP_047300454.1, XP_047300453.1, XP_047300455.1, NP_004395.1, NP_001008492.1, NP_001336220.1, NP_006146.1, NP_001008491.1, XP_054198243.1, XP_054198245.1, XP_054198242.1, NP_001307963.1, XP_054198244.1, NP_001307964.1, NP_001307960.1, NP_001307961.1, NP_001307962.1, NP_001269902.1, NP_001269901.1

OpenTargets

ENSG00000168385

ENSEMBL

ENSP00000385109, ENSP00000353157, ENST00000402092, ENSP00000479861, ENSP00000375832, ENSP00000375834, ENSP00000385172, ENSG00000168385, ENST00000360051, ENST00000616972, ENST00000391971, ENST00000401990, ENST00000391973

HPA

ENSG00000168385-SEPTIN2

GeneCards

SEPTIN2

PRO

Q15019

Pharos - Targets

Q15019

GlyGen

Q15019

PDB

7M6J, 6UPR, 6UPQ, 2QA5, 6UPA, 2QAG, 2QNR

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14141 SEPT6			0.953	23
UniProt:Q16181 SEPTIN7	1	SEPT7 [cytosol] (R-HSA-5692671)	0.86	14
UniProt:Q9UHD8 SEPT9			0.836	12
UniProt:Q99719 SEPT5			0.801	7
UniProt:Q9NVA2 SEP11			0.744	6
UniProt:Q92599 SEPT8			0.669	5
UniProt:Q8IYM1 SEP12			0.649	9
UniProt:Q9UH03 SEPT3			0.643	5
UniProt:Q9H8W4 PKHF2			0.556	3
UniProt:Q6ZU15 SEP14			0.547	2
UniProt:Q9P0V9 SEP10			0.527	3
UniProt:P49796 RGS3	1	RGS3 [plasma membrane] (R-HSA-8849410)	0.527	3
ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE			0.462	2
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE			0.462	2

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