Reactome | IFT140 [ciliary tip]

IFT140 [ciliary tip]

Stable Identifier

R-HSA-5625345

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary tip

Synonyms

IFT A 140

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96RY7 IFT140

Gene Names

IFT140, KIAA0590, WDTC2

Chain

chain:1-1462

Reference Genes

BioGPS Gene:9742 IFT140

COSMIC (genes):IFT140 IFT140

CTD Gene:9742 IFT140

dbSNP Gene:9742 IFT140

ENSEMBL:ENSG00000187535 IFT140

HGNC:29077 IFT140

KEGG:hsa:9742 IFT140

Monarch:9742 IFT140

NCBI Gene:9742 IFT140

OMIM:614620 IFT140

UCSC:Q96RY7 IFT140

Reference Transcript

Other Identifiers

11726874_a_at

11746735_a_at

11749489_a_at

16822762

204792_PM_s_at

204792_s_at

244585_PM_at

244585_at

3676001

3676003

3676004

3676006

3676007

3676009

3676010

3676011

3676012

3676013

3676014

3676015

3676016

3676017

3676018

3676019

3676020

3676023

3676025

3676026

3676027

3676028

3676032

3676034

3676035

3676036

3676037

3676038

3676039

3676040

3676041

3676043

3676044

3676046

3676047

3676048

3676049

3676050

3676051

3676052

3676053

3676054

3676055

3676056

3676057

3676058

3676060

3676061

37437_at

7998542

91809_at

9742

A_23_P140725

GE53296

GO:0003674

GO:0005515

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0005929

GO:0005930

GO:0007018

GO:0007368

GO:0007507

GO:0008589

GO:0021532

GO:0030030

GO:0030991

GO:0031076

GO:0032391

GO:0035108

GO:0035721

GO:0035845

GO:0036064

GO:0042073

GO:0042733

GO:0042995

GO:0043226

GO:0044782

GO:0048701

GO:0048856

GO:0060271

GO:0061512

GO:0097542

GO:0097730

GO:0120199

GO:1902017

GO:1905515

GO:1990403

HMNXSV003025268

HMNXSV003029922

HMNXSV003038450

Hs.166909.0.A1_3p_at

Hs.166909.0.A1_3p_x_at

ILMN_1687037

PH_hs_0024499

TC16000755.hg

TC16000756.hg

TC16001740.hg

g7662193_3p_s_at

p25961

Participates

as a component of

IFT A [ciliary tip] (Homo sapiens)

Other forms of this molecule

IFT140 [cilium]

Inferred To

ift140 [ciliary tip] (Xenopus tropicalis)

IFT140 [ciliary tip] (Bos taurus)

IFT140 [ciliary tip] (Canis familiaris)

IFT140 [ciliary tip] (Gallus gallus)

IFT140 [ciliary tip] (Sus scrofa)

Ift140 [ciliary tip] (Mus musculus)

Ift140 [ciliary tip] (Rattus norvegicus)

che-11 [ciliary tip] (Caenorhabditis elegans)

Cross References

RefSeq

XP_006721053.1, XP_006721054.1, NP_055529.2, XP_016879399.1

OpenTargets

ENSG00000187535

ENSEMBL

ENSP00000406012, ENSP00000354895, ENST00000426508, ENST00000361339

HPA

ENSG00000187535-IFT140

PRO

Q96RY7

Pharos - Targets

Q96RY7

Orphanet

IFT140

PDB

8BBG, 8FH3, 8BBF, 8FGW

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.823	9
UniProt:Q9HBG6 IFT122	2	IFT122 [cilium] (R-HSA-5610379) IFT122 [ciliary tip] (R-HSA-5625346)	0.823	7
UniProt:Q8NEZ3 WDR19	2	WDR19 [ciliary tip] (R-HSA-5625347) WDR19 [cilium] (R-HSA-5610446)	0.78	9
UniProt:Q7Z4L5 TTC21B	2	TTC21B [ciliary tip] (R-HSA-5625349) TTC21B [cilium] (R-HSA-5610430)	0.638	3
UniProt:Q96FT9 IFT43	2	IFT43 [ciliary tip] (R-HSA-5625348) IFT43 [cilium] (R-HSA-5617619)	0.638	4
UniProt:Q9Y2S2 CRYL1	1	CRYL1 [cytosol] (R-HSA-5661279)	0.527	2
UniProt:Q96FT9-2 IFT43			0.527	3
UniProt:Q86VG3 IFTAP			0.527	3
UniProt:Q99689 FEZ1			0.527	2
UniProt:O00295 TULP2			0.527	3
UniProt:Q99615 DNAJC7	2	DNAJC7 [nucleoplasm] (R-HSA-5255408) DNAJC7 [cytosol] (R-HSA-5252099)	0.527	2
UniProt:Q9P2L0 WDR35	2	WDR35 [ciliary tip] (R-HSA-5625351) WDR35 [cilium] (R-HSA-5610448)	0.508	2
UniProt:Q9BSD7 NTPCR			0.508	2
UniProt:O95573 ACSL3	2	ACSL3 [mitochondrial outer membrane] (R-HSA-9632656) ACSL3 [endoplasmic reticulum membrane] (R-HSA-548787)	0.508	2
UniProt:Q9BPW8 NIPS1			0.508	2
UniProt:Q9UG56 PISD	2	PISD(1-377) [mitochondrial inner membrane] (R-HSA-1500671) PISD(378-409) [mitochondrial inner membrane] (R-HSA-1500670)	0.508	2