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ub-SHH(24-462) W117G

Stable Identifier
R-HSA-5387345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Sonic hedgehog protein precursor, SHH, SHH_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16282375 Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly Proc. Natl. Acad. Sci. U.S.A. 2005
External Reference Information
External Reference
Gene Names
SHH
Chain
signal peptide:1-23, chain:24-462, chain:24-197
Reference Transcript
Other Identifiers
0002970504
11738265_at
17064810
207586_at
236263_at
3081218
3081219
3081220
3081221
3081222
3081223
3081224
3081225
3081226
3081227
3081229
3081230
3081231
31724_at
3HO5
3M1N
3MXW
59360_at
6469
70121_at
8144078
A_23_P111657
AAA62179
AAB67604
AAQ87879
AAS01990
AC002484
AC078834
AY422195
CCDS5942
CH236954
EAL23913
ENSG00000164690
ENSP00000297261
ENST00000297261
EntrezGene:6469
g4506938_3p_at
GE619667
GO:0000122
GO:0001525
GO:0001569
GO:0001570
GO:0001656
GO:0001658
GO:0001708
GO:0001755
GO:0001822
GO:0001942
GO:0001944
GO:0001947
GO:0002052
GO:0002053
GO:0002076
GO:0002320
GO:0003140
GO:0005113
GO:0005509
GO:0005515
GO:0005539
GO:0005576
GO:0005578
GO:0005615
GO:0005788
GO:0005829
GO:0005886
GO:0006355
GO:0006508
GO:0006897
GO:0007224
GO:0007228
GO:0007267
GO:0007275
GO:0007368
GO:0007389
GO:0007398
GO:0007405
GO:0007411
GO:0007417
GO:0007418
GO:0007442
GO:0007507
GO:0007596
GO:0008209
GO:0008233
GO:0008270
GO:0008283
GO:0008284
GO:0009790
GO:0009880
GO:0009949
GO:0009952
GO:0009953
GO:0009986
GO:0010463
GO:0010468
GO:0010469
GO:0010628
GO:0010629
GO:0014003
GO:0014706
GO:0014858
GO:0014902
GO:0016015
GO:0016020
GO:0016539
GO:0016787
GO:0021513
GO:0021522
GO:0021794
GO:0021871
GO:0021904
GO:0021924
GO:0021930
GO:0021938
GO:0021940
GO:0021978
GO:0030010
GO:0030162
GO:0030177
GO:0030178
GO:0030323
GO:0030324
GO:0030326
GO:0030336
GO:0030539
GO:0030850
GO:0030878
GO:0030900
GO:0030901
GO:0030902
GO:0031016
GO:0031069
GO:0032435
GO:0033077
GO:0033089
GO:0033092
GO:0034244
GO:0034504
GO:0035115
GO:0035116
GO:0042127
GO:0042130
GO:0042177
GO:0042307
GO:0042475
GO:0042476
GO:0042481
GO:0042733
GO:0043010
GO:0043066
GO:0043237
GO:0043369
GO:0043588
GO:0045059
GO:0045060
GO:0045109
GO:0045121
GO:0045165
GO:0045445
GO:0045596
GO:0045597
GO:0045880
GO:0045893
GO:0045944
GO:0046638
GO:0046639
GO:0046872
GO:0048468
GO:0048538
GO:0048546
GO:0048557
GO:0048568
GO:0048589
GO:0048598
GO:0048617
GO:0048643
GO:0048645
GO:0048646
GO:0048663
GO:0048706
GO:0048709
GO:0048714
GO:0048754
GO:0048839
GO:0048856
GO:0048859
GO:0048864
GO:0051146
GO:0051155
GO:0051781
GO:0060020
GO:0060021
GO:0060070
GO:0060173
GO:0060174
GO:0060425
GO:0060428
GO:0060438
GO:0060439
GO:0060441
GO:0060442
GO:0060445
GO:0060447
GO:0060458
GO:0060459
GO:0060463
GO:0060484
GO:0060516
GO:0060523
GO:0060662
GO:0060664
GO:0060684
GO:0060685
GO:0060738
GO:0060768
GO:0060769
GO:0060782
GO:0060783
GO:0060840
GO:0060916
GO:0061053
GO:0061189
GO:0071285
GO:0071542
GO:0072001
GO:0072136
GO:0090090
GO:0090370
GO:0097190
GO:1900175
GO:1900180
GO:1904339
GO:1905327
GO:2000062
GO:2000063
GO:2000357
GO:2000358
GO:2000729
GO:2001054
HGNC:10848
Hs.164537.0.A1_3p_at
Hs.738995
ILMN_1652693
IPR000320
IPR001657
IPR001767
IPR003586
IPR003587
IPR006141
IPR009045
IPR028992
L38518
MIM:142945
MIM:147250
MIM:269160
MIM:600725
MIM:611638
NM_000193
NP_000184
PF01079
PF01085
PH_hs_0006769
PH_hs_0009949
PR00632
SHH
SHH-201
SM00305
SM00306
TC07002064.hg
uc003wmk.2
UPI0000135942
Participant Of
Other forms of this molecule
Modified Residues
Name
L-tryptophan 117 replaced with glycine
Coordinate
117
PsiMod HEY
A protein modification that effectively removes or replaces an L-tryptophan.
A protein modification that effectively converts a source amino acid residue to a glycine.
Name
ubiquitinylated lysine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Disease
Name Identifier Synonyms
holoprosencephaly 4621 Holoprosencephaly sequence (disorder)
Cross References
RefSeq
ZINC - World Drugs
ZINC - FDA approved
ZINC - Substances
GeneCards
DOCK Blaster
ZINC target
ZINC - Biogenic
PRO
Orphanet
ZINC - Predictions - Purchasable
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96QV1 HHIP  1 0.691 10