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Me2aR30-HIST1H2AB [nucleoplasm]
Stable Identifier
R-HSA-5244538
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST1H2AB
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
RMTs methylate histone arginines (Homo sapiens)
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Homo sapiens)
Me2aR30-histone H2A, MeR30-histone H2A [nucleoplasm] (Homo sapiens)
Me2aR30-histone H2A [nucleoplasm] (Homo sapiens)
Me2aR30-histone HIST1H2A [nucleoplasm] (Homo sapiens)
Me2aR30-HIST1H2AB [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04908 H2AC4
Gene Names
H2AC4, H2AFM, HIST1H2AB, H2AC8, H2AFA, HIST1H2AE
Chain
initiator methionine:, chain:2-130
Reference Genes
BioGPS Gene:3012 H2AC4
BioGPS Gene:8335 H2AC4
COSMIC (genes):HIST1H2AB H2AC4
COSMIC (genes):HIST1H2AE H2AC4
CTD Gene:3012 H2AC4
CTD Gene:8335 H2AC4
dbSNP Gene:3012 H2AC4
dbSNP Gene:8335 H2AC4
ENSEMBL:ENSG00000277075 HIST1H2AE
ENSEMBL:ENSG00000278463 HIST1H2AB
HGNC:4724 H2AC4
HGNC:4734 H2AC4
KEGG:hsa:3012 H2AC4
KEGG:hsa:8335 H2AC4
Monarch:3012 H2AC4
Monarch:8335 H2AC4
NCBI Gene:3012 H2AC4
NCBI Gene:8335 H2AC4
OMIM:602786 H2AC4
OMIM:602795 H2AC4
UCSC:P04908 H2AC4
Reference Transcript
RefSeq:NM_021052.2 H2AC4
RefSeq:NM_003513.2 H2AC4
Other Identifiers
11731693_at
11731694_s_at
11741215_at
17005589
17016366
208569_PM_at
208569_at
214469_PM_at
214469_at
2899224
2899225
2899226
2899228
2899230
2946220
2946221
2946222
2946223
2946224
3012
35127_at
8117408
8124391
8335
A_14_P115530
A_23_P59045
A_24_P223384
GE504811
GE62562
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005634
GO:0005694
GO:0006325
GO:0008285
GO:0030527
GO:0031492
GO:0031507
GO:0043226
GO:0043229
GO:0043505
GO:0046982
GO:0061644
GO:0070062
HMNXSV003010811
HMNXSV003012591
Hs.121017.0.S1_3p_at
ILMN_1753524
ILMN_1756849
M60752_at
PH_hs_0006702
PH_hs_0013174
PH_hs_0032313
TC06000173.hg
TC06001343.hg
Z83741_at
g4504246_3p_at
Participates
as a member of
Me2aR30-histone HIST1H2A [nucleoplasm] (Homo sapiens)
Other forms of this molecule
HIST1H2AB [nucleoplasm]
Ack-HIST1H2AB [nucleoplasm]
HIST1H2AB [extracellular region]
MeR12-HIST1H2AB [nucleoplasm]
Me2aR12-HIST1H2AB [nucleoplasm]
Me2sR4-HIST1H2AB [nucleoplasm]
MeR4-HIST1H2AB [nucleoplasm]
Me2aR4-HIST1H2AB [nucleoplasm]
MeR30-HIST1H2AB [nucleoplasm]
Ack6-HIST1H2AB [nucleoplasm]
Ub-HIST1H2AB [nucleoplasm]
K63polyUb-HIST1H2AB [nucleoplasm]
Inferred To
LOC100485548 [nucleoplasm]
(Xenopus tropicalis)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Caenorhabditis elegans)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Danio rerio)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Drosophila melanogaster)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Mus musculus)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of Me2aR30-HIST1H2AB [nucleoplasm]
(Xenopus tropicalis)
LOC100487632 [nucleoplasm]
(Xenopus tropicalis)
LOC116411633 [nucleoplasm]
(Xenopus tropicalis)
Hist1h2ap [nucleoplasm]
(Mus musculus)
his-35 [nucleoplasm]
(Caenorhabditis elegans)
HTA1 [nucleoplasm]
(Saccharomyces cerevisiae)
HTA2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Av2 [nucleoplasm]
(Dictyostelium discoideum)
His2A:CG33862 [nucleoplasm]
(Drosophila melanogaster)
H2ac10 [nucleoplasm]
(Rattus norvegicus)
Hist1h2ao [nucleoplasm]
(Mus musculus)
hta1 [nucleoplasm]
(Schizosaccharomyces pombe)
Me2aR30-HIST1H2AB [nucleoplasm]
(Bos taurus)
Me2aR30-HIST1H2AB [nucleoplasm]
(Gallus gallus)
Me2aR30-HIST1H2AB [nucleoplasm]
(Plasmodium falciparum)
Hist1h2af [nucleoplasm]
(Mus musculus)
H2ac12 [nucleoplasm]
(Mus musculus)
his-65 [nucleoplasm]
(Caenorhabditis elegans)
hta2 [nucleoplasm]
(Schizosaccharomyces pombe)
h2ac16 [nucleoplasm]
(Xenopus tropicalis)
H2AC4 [nucleoplasm]
(Canis familiaris)
LOC116407737 [nucleoplasm]
(Xenopus tropicalis)
LOC100487067 [nucleoplasm]
(Xenopus tropicalis)
h2ax1 [nucleoplasm]
(Danio rerio)
H2ac4 [nucleoplasm]
(Mus musculus)
zgc:56685 [nucleoplasm]
(Danio rerio)
H2ac6 [nucleoplasm]
(Mus musculus)
Hist1h2an [nucleoplasm]
(Mus musculus)
H2AC8 [nucleoplasm]
(Sus scrofa)
H2ac15 [nucleoplasm]
(Mus musculus)
H2AX [nucleoplasm]
(Dictyostelium discoideum)
H2Av3 [nucleoplasm]
(Dictyostelium discoideum)
htas-1 [nucleoplasm]
(Caenorhabditis elegans)
H2Av1 [nucleoplasm]
(Dictyostelium discoideum)
H2ac8 [nucleoplasm]
(Mus musculus)
H2ac11 [nucleoplasm]
(Mus musculus)
LOC101732059 [nucleoplasm]
(Xenopus tropicalis)
His2A:CG33859 [nucleoplasm]
(Drosophila melanogaster)
Modified Residues
Name
asymmetric dimethyl-L-arginine at 30
Coordinate
30
PsiMod Name
asymmetric dimethyl-L-arginine
PsiMod Definition
A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine.
Cross References
RefSeq
NP_003504.2
,
NP_066390.1
OpenTargets
ENSG00000278463
,
ENSG00000277075
ENSEMBL
ENSP00000483842
,
ENSP00000303373
,
ENST00000615868
,
ENST00000303910
HPA
ENSG00000277075-H2AC8
,
ENSG00000278463-H2AC4
PRO
P04908
Pharos - Targets
P04908
GlyGen
P04908
HMDB Protein
HMDBP07727
PDB
7W9V
,
3AZE
,
8SN4
,
6L9H
,
6IQ4
,
3WTP
,
8HAH
,
5XF3
,
7XD0
,
8HAN
,
8UQD
,
5X7X
,
8UQB
,
5ZBX
,
5GTC
,
7CCR
,
6V2K
,
5AV5
,
8Q3M
,
6O1D
,
6T79
,
6J4Y
,
6JR0
,
8HE5
,
6LA9
,
7SCZ
,
7XX6
,
8IEJ
,
7PEW
,
7PFF
,
4YM5
,
8JCD
,
7PFX
,
8SNA
,
6HKT
,
7XZZ
,
6IR9
,
7Y00
,
7K61
,
5XF4
,
6E0P
,
8H0W
,
8Q36
,
6INQ
,
8SN1
,
5AVB
,
8UQC
,
5AV8
,
5Y0D
,
6J50
,
6T7A
,
7VA4
,
8IHL
,
7DBP
,
7PEX
,
6A5T
,
6J51
,
7XX5
,
7PFC
,
8OSL
,
7PEV
,
7XVM
,
8JCC
,
7NL0
,
8JBX
,
3AV1
,
3AYW
,
8W9F
,
5B24
,
7XSE
,
7LYA
,
8U14
,
7K60
,
8HR1
,
7D20
,
8HAG
,
8UQ9
,
7XT7
,
8HAM
,
7COW
,
8Q3X
,
5AV9
,
8SN0
,
7CCQ
,
5Z23
,
7ZI4
,
8JNF
,
6JR1
,
7PEZ
,
6LE9
,
6USJ
,
7PF2
,
6A5U
,
6V92
,
7SCY
,
7V9C
,
6R8Z
,
6R93
,
6M3V
,
8XBU
,
8OSK
,
7PFE
,
8SN8
,
3X1S
,
2RVQ
,
3AZK
,
8GRM
,
8TXX
,
8W9E
,
8SN3
,
7C0M
,
6AEE
,
2CV5
,
3AZN
,
8H0V
,
7XD1
,
5CPI
,
5Y0C
,
8HAJ
,
5AVC
,
5AV6
,
3A6N
,
6J4W
,
6T7B
,
8Q3E
,
6LA2
,
6LA8
,
7Y7I
,
6R8Y
,
6BUZ
,
6A5R
,
6R94
,
8IEG
,
7PFT
,
7PFW
,
3AZJ
,
8SMW
,
8TXW
,
8W9D
,
7XZY
,
7LYC
,
6YOV
,
3W99
,
7BXT
,
7XTI
,
5AY8
,
7V90
,
3AZM
,
7D1Z
,
7XSZ
,
8HQY
,
8SN2
,
7WBW
,
8JNE
,
8OTS
,
5B2I
,
7V9S
,
6HTS
,
6ACL
,
6A5P
,
7PF4
,
5B40
,
7PFA
,
8I17
,
7PF6
,
5B0Y
,
7BWD
,
7PFV
,
8XBT
,
3AZI
,
8SN7
,
3AZG
,
8TXV
,
7LYB
,
6LER
,
7K5X
,
8SMZ
,
5JRG
,
8UQ8
,
7V96
,
7XSX
,
3W98
,
5GXQ
,
8HAI
,
7XTD
,
3AZL
,
8U13
,
7WBV
,
6T7C
,
6J4Z
,
5B2J
,
8OTT
,
6T90
,
6A5O
,
4Z5T
,
6LAB
,
7PF3
,
8JH3
,
6R91
,
7PEU
,
6M44
,
8OSJ
,
7PFU
,
3AZH
,
8SMY
,
5GSE
,
3AZF
,
8SN6
,
8WG5
,
8JLB
,
7K63
,
7VCL
,
7K5Y
,
3W97
,
8G57
,
7V99
,
8UQA
,
8HAL
,
7XZX
,
5CPJ
,
6E0C
,
5B32
,
7XCR
,
8YTI
,
8JND
,
6T93
,
7V9K
,
6A5L
,
7XVL
,
6L4A
,
8JH2
,
6R92
,
7PF0
,
7PF5
,
5B0Z
,
6L9Z
,
3X1V
,
3WKJ
,
8JLA
,
8SMX
,
6IPU
,
3AN2
,
8KB5
,
8SN5
,
8JLD
,
3AFA
,
5XF5
,
8UQE
,
6KE9
,
6L49
,
7VZ4
,
3W96
,
7XCT
,
5CPK
,
7BY0
,
8HAK
,
8JL9
,
8UPF
,
5B31
,
7WBX
,
6T7D
,
7PEY
,
6J4X
,
7V9J
,
7PFD
,
8JH4
,
4YM6
,
6JXD
,
7PET
,
6R90
,
3AV2
,
8JHG
,
6KXV
,
8SN9
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62805 H4C1
17
HIST1H4 [nucleoplasm]
(R-HSA-181902)
Me2K21-HIST1H4 [nucleoplasm]
(R-HSA-5651652)
MeK21-HIST1H4 [nucleoplasm]
(R-HSA-5423110)
AcK-HIST1H4 [nucleoplasm]
(R-HSA-3451124)
AcK9-HIST1H4 [nucleoplasm]
(R-HSA-4568758)
AcK6-HIST1H4 [nucleoplasm]
(R-HSA-4568748)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-427469)
HIST1H4A [extracellular region]
(R-HSA-977569)
Me3K21-HIST1H4 [nucleoplasm]
(R-HSA-5651656)
MeR4-HIST1H4 [nucleoplasm]
(R-HSA-4754240)
Me2sR4-HIST1H4 [nucleoplasm]
(R-HSA-4754243)
Me2aR4-HIST1H4 [nucleoplasm]
(R-HSA-5229015)
AcK13-HIST1H4 [nucleoplasm]
(R-HSA-4568744)
AcK5,12-HIST1H4A [nucleoplasm]
(R-HSA-212078)
4xAcK-HIST1H4A [nucleoplasm]
(R-HSA-427390)
monoSUMO1-HIST1H4 [nucleoplasm]
(R-HSA-4570518)
polySUMO3-HIST1H4 [nucleoplasm]
(R-HSA-4570531)
0.874
12
UniProt:Q16695 H3-4
3
Me2K5-HIST3H3 [nucleoplasm]
(R-HSA-2245186)
Me3K5-HIST3H3 [nucleoplasm]
(R-HSA-2245188)
HIST3H3 [nucleoplasm]
(R-HSA-181914)
0.589
2
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