botA HC:LC dimer:SV2:GT1b [plasma membrane]

Stable Identifier
R-HSA-5244411
Type
Complex
Species
Homo sapiens
Related Species
Clostridium botulinum
Compartment
plasma membrane
Synonyms
BoNT/A:SV2:GT1b
GO Cellular Component
host cell plasma membrane (0020002)
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
16543415 SV2 is the protein receptor for botulinum neurotoxin A

Tepp, WH, Chapman, ER, Janz, R, Dean, C, Yeh, F, Dong, M, Johnson, EA

Science 2006
9712688 Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins

Mochida, S, Kamata, Y, Kozaki, S, Nishiki, T, Watarai, S

Microb. Pathog. 1998
Participants
components
Participates
as an output of
as an input of
Disease
Name Identifier Synonyms
botulism DOID:11976 Botulism (disorder), Intoxication with Clostridium botulinum toxin, Botulism, Infection due to clostridium botulinum, Botulism, Foodborne botulism, botulism, Botulism, Botulism, Botulism, Food poisoning due to Clostridium botulinum, Botulism poisoning
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