Reactome | AEBP2 [nucleoplasm]

AEBP2 [nucleoplasm]

Stable Identifier

R-HSA-5082342

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger protein AEBP2, AEBP2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6ZN18 AEBP2

Gene Names

AEBP2

Chain

initiator methionine:, chain:2-517

Reference Genes

BioGPS Gene:121536 AEBP2

COSMIC (genes):AEBP2 AEBP2

CTD Gene:121536 AEBP2

dbSNP Gene:121536 AEBP2

ENSEMBL:ENSG00000139154 AEBP2

HGNC:24051 AEBP2

KEGG:hsa:121536 AEBP2

Monarch:121536 AEBP2

NCBI Gene:121536 AEBP2

OMIM:617934 AEBP2

UCSC:Q6ZN18 AEBP2

Reference Transcript

Participates

as a component of

PRC2 (EZH2) Core:AEBP2 [nucleoplasm] (Homo sapiens)

Inferred To

jing [nucleoplasm] (Drosophila melanogaster)

AEBP2 [nucleoplasm] (Bos taurus)

AEBP2 [nucleoplasm] (Canis familiaris)

AEBP2 [nucleoplasm] (Gallus gallus)

AEBP2 [nucleoplasm] (Sus scrofa)

aebp2 [nucleoplasm] (Danio rerio)

aebp2 [nucleoplasm] (Xenopus tropicalis)

Aebp2 [nucleoplasm] (Mus musculus)

Aebp2 [nucleoplasm] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000398864, ENSP00000381840, ENST00000266508, ENSP00000354267, ENST00000360995, ENSP00000266508, ENSG00000139154

OpenTargets

ENSG00000139154

GeneCards

AEBP2

HPA

ENSG00000139154-AEBP2

PRO

Q6ZN18

Pharos - Targets

Q6ZN18

PDB

8FYH, 5Y0U, 5WAI, 8EQV, 7KSO, 8T9G, 5Y1U, 6WKR, 9C8U, 8TB9, 6C24, 6C23, 8TAS

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15022 SUZ12	2	SUZ12 [nucleoplasm] (R-HSA-212217) monoSUMO1-K75-SUZ12 [nucleoplasm] (R-HSA-4615932)	0.881	10
UniProt:Q15910 EZH2	1	EZH2 [nucleoplasm] (R-HSA-212298)	0.793	8
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.731	7
UniProt:O75530 EED	1	EED [nucleoplasm] (R-HSA-212278)	0.648	5
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.643	5

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