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AcK6-HIST2H2AB [nucleoplasm]
Stable Identifier
R-HSA-4568609
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
AcK6-histone H2A [nucleoplasm] (Homo sapiens)
AcK6-histone HIST2H2A [nucleoplasm] (Homo sapiens)
AcK6-HIST2H2AB [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IUE6 H2AC21
Gene Names
H2AC21, HIST2H2AB
Chain
initiator methionine:, chain:2-130
Reference Genes
BioGPS Gene:317772 H2AC21
CTD Gene:317772 H2AC21
dbSNP Gene:317772 H2AC21
ENSEMBL:ENSG00000184270 HIST2H2AB
ENSEMBL_homo_sapiens_GENE:ENSG00000184270.6 H2AC21
HGNC:20508 H2AC21
KEGG Gene (Homo sapiens):317772 H2AC21
Monarch:317772 H2AC21
NCBI Gene:317772 H2AC21
OMIM:615014 H2AC21
UCSC:Q8IUE6 H2AC21
Reference Transcript
RefSeq:NM_175065.2 H2AC21
Other Identifiers
11715148_s_at
11715149_x_at
11759284_at
16692636
2357932
2357955
2357956
2434088
2434131
2434132
2434133
2434134
317772
7919642
ADDON002783.hg
A_23_P343927
A_24_P68631
GE508529
GO:0000786
GO:0003674
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005694
GO:0008150
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0070062
HMNXSV003048996
ILMN_1747589
PH_hs_0020211
TC01003194.hg
Participates
as a member of
AcK6-histone HIST2H2A [nucleoplasm] (Homo sapiens)
Other forms of this molecule
AcK-HIST2H2AB [nucleoplasm]
HIST2H2AB [nucleoplasm]
MeR12-HIST2H2AB [nucleoplasm]
Me2aR12-HIST2H2AB [nucleoplasm]
MeR4-HIST2H2AB [nucleoplasm]
Me2aR4-HIST2H2AB [nucleoplasm]
MeR30-HIST2H2AB [nucleoplasm]
Me2aR30-HIST2H2AB [nucleoplasm]
Ub-HIST2H2AB [nucleoplasm]
K63polyUb-HIST2H2AB [nucleoplasm]
Inferred To
LOC100485548 [nucleoplasm]
(Xenopus tropicalis)
H2AC21 [nucleoplasm]
(Canis familiaris)
LOC100487632 [nucleoplasm]
(Xenopus tropicalis)
LOC116411633 [nucleoplasm]
(Xenopus tropicalis)
h2ac16 [nucleoplasm]
(Xenopus tropicalis)
LOC116407737 [nucleoplasm]
(Xenopus tropicalis)
LOC100487067 [nucleoplasm]
(Xenopus tropicalis)
h2ax1 [nucleoplasm]
(Danio rerio)
Ack6-HIST1H2AB [nucleoplasm]
(Plasmodium falciparum)
HTA1 [nucleoplasm]
(Saccharomyces cerevisiae)
HTA2 [nucleoplasm]
(Saccharomyces cerevisiae)
AcK6-HIST2H2AB [nucleoplasm]
(Bos taurus)
AcK6-HIST2H2AB [nucleoplasm]
(Sus scrofa)
H2AFX [nucleoplasm]
(Gallus gallus)
H2AX [nucleoplasm]
(Dictyostelium discoideum)
His2A:CG33862 [nucleoplasm]
(Drosophila melanogaster)
hta1 [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of AcK6-HIST2H2AB [nucleoplasm]
(Xenopus tropicalis)
Homologues of Ack6-HIST1H2AB [nucleoplasm]
(Saccharomyces cerevisiae)
Modified Residues
Name
N6-acetyl-L-lysine at 6
Coordinate
6
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_778235.1
OpenTargets
ENSG00000184270
HPA
ENSG00000184270-H2AC21
GeneCards
Q8IUE6
Ensembl
ENSP00000332790
,
ENST00000331128
,
ENSG00000184270
PRO
Q8IUE6
Pharos - Targets
Q8IUE6
HMDB Protein
HMDBP07730
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17096 HMGA1
2
HMGA1 [cytosol]
(R-HSA-3004619)
HMGA1 [nucleoplasm]
(R-HSA-3004623)
0.669
3
UniProt:P62241 RPS8
2
RPS8 [nucleoplasm]
(R-HSA-6791203)
RPS8 [cytosol]
(R-HSA-72385)
0.527
2
UniProt:P16104 H2AFX
7
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
H2AFX [nucleoplasm]
(R-HSA-56151)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
H2AFX [extracellular region]
(R-HSA-977583)
0.527
3
UniProt:Q08945 SSRP1
1
SSRP1 [nucleoplasm]
(R-HSA-65105)
0.527
2
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