Acetylation of glucosamine 6-phosphate to GlcNAc6P

Stable Identifier
R-HSA-449734
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytosolic GNPNAT1 catalyzes the reaction of glucosamine 6-phosphate and acetyl-CoA to form N-acetyl-glucosamine 6-phosphate (GlcNAc6P) and CoA-SH. Structural studies indicate that the active form of the enzyme is a dimer (Wang J et al, 2008).

Literature References
PubMed ID Title Journal Year
18675810 Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1

Wang, J, Liu, X, Liang, YH, Li, LF, Su, XD

FEBS Lett 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glucosamine 6-phosphate N-acetyltransferase activity of 2xGNPNAT1 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created