CD151 interacts with BP180 and the integrin alpha 6 subunit

Stable Identifier
R-HSA-446083
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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CD151 interacts with BP180 and the integrin alpha 6 subunit
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CD151 interacts with the extracellular domain of the integrin alpha 6 subunit. CD151 is thought to play a role in the formation and stability of hemidesmosomes by providing a framework for the spatial organization of the hemidesmosomal components (Sterk et al., 2000).
Literature References
PubMed ID Title Journal Year
10811835 The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes

Geuijen, CA, Oomen, LC, Calafat, J, Sonnenberg, A, Janssen, H, Sterk, LM

J Cell Biol 2000
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Orthologous Events
CD151 interacts with BP180 and the integrin alpha 6 subunit (Bos taurus)
CD151 interacts with BP180 and the integrin alpha 6 subunit (Canis familiaris)
CD151 interacts with BP180 and the integrin alpha 6 subunit (Mus musculus)
CD151 interacts with BP180 and the integrin alpha 6 subunit (Rattus norvegicus)
CD151 interacts with BP180 and the integrin alpha 6 subunit (Sus scrofa)
Authored
Matthews, L  (2009-11-04)
Reviewed
Sonnenberg, A  (2009-11-15)
Created
Matthews, L  (2009-11-09)
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