PXLP-K-SPTLC1 [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-428155
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
serine palmitoyltransferase 1
Icon
PXLP-K-SPTLC1 [endoplasmic reticulum membrane] icon
PXLP-K-SPTLC1 [endoplasmic reticulum membrane] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:O15269 SPTLC1
Gene Names
SPTLC1, LCB1
Chain
chain:1-473
Reference Genes
BioGPS Gene:10558 SPTLC1
COSMIC (genes):SPTLC1 SPTLC1
CTD Gene:10558 SPTLC1
dbSNP Gene:10558 SPTLC1
ENSEMBL:ENSG00000090054 SPTLC1
ENSEMBL:ENSG00000090054.16 SPTLC1
HGNC:11277 SPTLC1
KEGG Gene (Homo sapiens):10558 SPTLC1
Monarch:10558 SPTLC1
NCBI Gene:10558 SPTLC1
OMIM:605712 SPTLC1
UCSC:O15269 SPTLC1
Reference Transcript
Other Identifiers
10558
11731838_at
11740250_a_at
11740251_a_at
11752171_s_at
1554053_3p_at
1554053_PM_at
1554053_at
17095744
202277_PM_at
202277_at
202278_PM_s_at
202278_s_at
2359228
2359229
2486868
2911845
2945409
3091226
3091227
3176769
3214588
3214589
3214590
3214591
3214592
3214593
3214594
3214595
3214598
3214600
3214601
3214602
3214603
3214607
3214611
3214612
3214613
3214615
3214616
3214617
3214619
3214621
3214632
3214633
3214634
3214637
3214638
3241332
3241333
3241334
3494692
3494693
3663618
3663620
38818_at
77411_at
8162294
A_23_P311192
A_23_P43326
GE60256
GO:0003824
GO:0004758
GO:0005515
GO:0005783
GO:0005789
GO:0006629
GO:0006665
GO:0006686
GO:0006914
GO:0009058
GO:0012501
GO:0016020
GO:0016740
GO:0016746
GO:0017059
GO:0030148
GO:0030170
GO:0035339
GO:0043226
GO:0046511
GO:0046512
GO:0046513
GO:1904504
GO:1904649
HMNXSV003001607
Hs.90458.0.S2_3p_at
ILMN_1665094
ILMN_1799853
ILMN_1813491
ILMN_2249473
ILMN_2274420
PH_hs_0022206
TC09001328.hg
g5454083_3p_a_at
Participates
as a component of
Inferred To
Spt-I [endoplasmic reticulum membrane] (Drosophila melanogaster)
Sptlc1 [endoplasmic reticulum membrane] (Mus musculus)
Sptlc1 [endoplasmic reticulum membrane] (Rattus norvegicus)
sptlc1 [endoplasmic reticulum membrane] (Xenopus tropicalis)
SPTLC1 [endoplasmic reticulum membrane] (Bos taurus)
SPTLC1 [endoplasmic reticulum membrane] (Sus scrofa)
PXLP-K-SPTLC1 [endoplasmic reticulum membrane] (Canis familiaris)
PXLP-K-SPTLC1 [endoplasmic reticulum membrane] (Danio rerio)
PXLP-K-SPTLC1 [endoplasmic reticulum membrane] (Gallus gallus)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at unknown position
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (2)
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