Reactome | Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm]

Chromatin (H3K9me2, 5mC):MBD2

Stable Identifier

R-HSA-427343

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
14610093	Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression	J Biol Chem	2004

Participants

components

Participant Of

output

MBD2 binds methylcytosine in chromatin

This entity regulates

Negative Regulation

'Methylcytosine: MBD2 Complex [nucleoplasm]' negatively regulates 'UBF-1 Binds rDNA Promoter'

Inferred To

Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Bos taurus)

Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Canis familiaris)

Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Drosophila melanogaster)

Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Mus musculus)

Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Rattus norvegicus)

Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Sus scrofa)

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