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PI3-kinase gamma, regulatory subunit [cytosol]
Stable Identifier
R-HSA-425644
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
CD28:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
ICOS:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
CD28:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
ICOS:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
GPVI-mediated activation cascade (Homo sapiens)
GPVI stimulates PI3K beta, gamma (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Homo sapiens)
PI3K alpha, beta, gamma [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Regulation of T cell activation by CD28 family (Homo sapiens)
Co-stimulation by CD28 (Homo sapiens)
CD28 dependent PI3K/Akt signaling (Homo sapiens)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
CD28:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
PI3K binds CD28 (Homo sapiens)
CD28:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Co-stimulation by ICOS (Homo sapiens)
PI3K binds ICOS (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
ICOS:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
CD28:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
ICOS:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
CD28:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
ICOS:PI3K [plasma membrane] (Homo sapiens)
Class 1A PI3Ks [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G-protein beta:gamma signalling (Homo sapiens)
G beta:gamma signalling through PI3Kgamma (Homo sapiens)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Homo sapiens)
G-protein beta-gamma:PI3K gamma [plasma membrane] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Gbeta:gamma recruits PI3K gamma (Homo sapiens)
G-protein beta-gamma:PI3K gamma [plasma membrane] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
PI3K gamma [cytosol] (Homo sapiens)
PI3-kinase gamma, regulatory subunit [cytosol] (Homo sapiens)
Participants
members
PIK3R5 [cytosol]
(Homo sapiens)
PIK3R6 [cytosol]
(Homo sapiens)
Participates
as a component of
PI3K gamma [cytosol] (Homo sapiens)
Inferred To
Ghost homologue of PI3-kinase gamma, regulatory subunit [cytosol]
(Drosophila melanogaster)
pik3r6 [cytosol]
(Xenopus tropicalis)
PI3-kinase gamma, regulatory subunit [cytosol]
(Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol]
(Canis familiaris)
PI3-kinase gamma, regulatory subunit [cytosol]
(Dictyostelium discoideum)
PI3-kinase gamma, regulatory subunit [cytosol]
(Gallus gallus)
PI3-kinase gamma, regulatory subunit [cytosol]
(Mus musculus)
PI3-kinase gamma, regulatory subunit [cytosol]
(Rattus norvegicus)
PI3-kinase gamma, regulatory subunit [cytosol]
(Sus scrofa)
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