Reactome | PARD6B [cytosol]

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PARD6B

Stable Identifier

R-HSA-419973

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Partitioning defective 6 homolog beta, PAR6B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BYG5 PARD6B

Gene Names

PARD6B, PAR6B

Chain

chain:1-372

Reference Genes

BioGPS Gene:84612 PARD6B

COSMIC (genes):PARD6B PARD6B

CTD Gene:84612 PARD6B

dbSNP Gene:84612 PARD6B

ENSEMBL:ENSG00000124171 PARD6B

HGNC:16245 PARD6B

KEGG Gene (Homo sapiens):hsa:84612 PARD6B

Monarch:84612 PARD6B

NCBI Gene:84612 PARD6B

OMIM:608975 PARD6B

UCSC:Q9BYG5 PARD6B

Reference Transcript

RefSeq:NM_032521.2 PARD6B

Other Identifiers

0001340497

11728587_a_at

11753786_a_at

13376

16914867

211907_s_at

214827_at

235165_at

32018_at

3888838

3888839

3888841

3888845

3888846

3888847

52525_r_at

77992_at

8063410

84612

A_14_P103128

A_32_P205637

A_33_P3227457

CCDS33485

ENSG00000124171

ENSP00000360672

ENSP00000379354

ENST00000371610

ENST00000396039

EntrezGene:84612

g13537116_3p_s_at

GE900849

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0005923

GO:0005938

GO:0006461

GO:0007043

GO:0007049

GO:0007163

GO:0007409

GO:0016020

GO:0016324

GO:0030054

GO:0030334

GO:0043234

GO:0045177

GO:0051301

GO:0070062

GO:0070830

HGNC:16245

HPA013376

Hs.265398.0.S1_3p_at

Hs.304918.0.S1_3p_at

Hs.589848

ILMN_1745154

MIM:608975

NM_032521

NP_115910

PARD6B

PARD6B-201

PARD6B-202

PF00564

PF00595

PH_hs_0015707

SM00228

SM00666

TC20000407.hg

uc002xvo.3

uc061xsm.1

UPI000006FA7C

UPI0000E5A33E

Participant Of

hasMember

PAR-6 [cytosol]

Other forms of this molecule

PARD6B [plasma membrane]

Inferred To

PARD6B [cytosol] (Bos taurus)

PARD6B [cytosol] (Canis familiaris)

PARD6B [cytosol] (Danio rerio)

PARD6B [cytosol] (Gallus gallus)

PARD6B [cytosol] (Mus musculus)

PARD6B [cytosol] (Rattus norvegicus)

PARD6B [cytosol] (Sus scrofa)

PARD6B [cytosol] (Taeniopygia guttata)

PARD6B [cytosol] (Xenopus tropicalis)

Homologues of PARD6B [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_115910.1

GeneCards

Q9BYG5

PRO

Q9BYG5

HMDB Protein

HMDBP08501

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P60953 CDC42	3	CDC42 [plasma membrane] (R-HSA-449545) CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086) CDC42 [cytosol] (R-HSA-442630)	0.89	12
UniProt:Q05513 PRKCZ	4	p-T410-PRKCZ [cytosol] (R-HSA-437181) PRKCZ [cell junction] (R-HSA-2134483) p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218)	0.864	9
UniProt:P41743 PRKCI	3	PRKCI [cytosol] (R-HSA-58206) PRKCI [nucleoplasm] (R-HSA-9021345) PRKCI [plasma membrane] (R-HSA-420005)	0.845	15
UniProt:P63000 RAC1	6	RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [plasma membrane] (R-HSA-351141) RAC1 [cytosol] (R-HSA-442615)	0.567	3
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:P04637 TP53	27	TP53 [cytosol] (R-HSA-8869337) Unfolded TP53 [cytosol] (R-HSA-6813797) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) SUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) Me2K-370,382-TP53 [nucleoplasm] (R-HSA-3222242) Me2-K373-TP53 [nucleoplasm] (R-HSA-6805759) MeK-370,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222226) p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (R-HSA-6804378) Me-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222124) Me1-K372,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805719) p-S37-TP53 [nucleoplasm] (R-HSA-3239022) p-S15,S392-TP53 [nucleoplasm] (R-HSA-3222015) p-S15,S20,S392-TP53 [nucleoplasm] (R-HSA-6805053) p-S15,S33,S46-TP53 [nucleoplasm] (R-HSA-6805268) p-T55-TP53 [nucleoplasm] (R-HSA-6805400) p-S15,S20,S46-TP53 [nucleoplasm] (R-HSA-6798369) p-S315-TP53 [nucleoplasm] (R-HSA-6805106) p-S15,S20,S269,T284-TP53 [nucleoplasm] (R-HSA-6805133) PolyUb,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6804446) Ac-K120,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805656) Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805631) Ac-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-5628868) PolyUb-TP53 [cytosol] (R-HSA-6793681) PolyUb-TP53 [nucleoplasm] (R-HSA-6793679) p-S15,S20-TP53 [nucleoplasm] (R-HSA-69683) p-S15-TP53 [nucleoplasm] (R-HSA-69507) TP53 [nucleoplasm] (R-HSA-69488)	0.488	2