Reactome | PARD6B [cytosol]

PARD6B [cytosol]

Stable Identifier

R-HSA-419973

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Partitioning defective 6 homolog beta, PAR6B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BYG5 PARD6B

Gene Names

PARD6B, PAR6B

Chain

chain:1-372

Reference Genes

BioGPS Gene:84612 PARD6B

COSMIC (genes):PARD6B PARD6B

CTD Gene:84612 PARD6B

dbSNP Gene:84612 PARD6B

ENSEMBL:ENSG00000124171 PARD6B

HGNC:16245 PARD6B

KEGG Gene (Homo sapiens):84612 PARD6B

Monarch:84612 PARD6B

NCBI Gene:84612 PARD6B

OMIM:608975 PARD6B

UCSC:Q9BYG5 PARD6B

Reference Transcript

RefSeq:NM_032521.2 PARD6B

Other Identifiers

0001340497

11728587_a_at

11753786_a_at

16914867

211907_s_at

214827_at

235165_at

32018_at

3888837

3888838

3888839

3888841

3888845

3888846

3888847

52525_r_at

77992_at

8063410

84612

A_14_P103128

A_32_P205637

A_33_P3227457

GE900849

GO:0000902

GO:0003674

GO:0005080

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0005923

GO:0005938

GO:0007010

GO:0007043

GO:0007049

GO:0007098

GO:0007163

GO:0007409

GO:0008150

GO:0016020

GO:0016324

GO:0019899

GO:0022607

GO:0030054

GO:0030154

GO:0030334

GO:0032991

GO:0034330

GO:0040011

GO:0043226

GO:0045177

GO:0048856

GO:0048870

GO:0051301

GO:0060341

GO:0065003

GO:0070062

GO:0070830

HMNXSV003001457

Hs.265398.0.S1_3p_at

Hs.304918.0.S1_3p_at

ILMN_1745154

PH_hs_0015707

TC20000407.hg

g13537116_3p_s_at

Participates

as a candidate of

RHOV effectors [cytosol] (Homo sapiens)

as a member of

PAR-6 [cytosol] (Homo sapiens)

Other forms of this molecule

PARD6B [plasma membrane]

Inferred To

pard6b [cytosol] (Danio rerio)

Pard6b [cytosol] (Mus musculus)

Pard6b [cytosol] (Rattus norvegicus)

PARD6B [cytosol] (Bos taurus)

PARD6B [cytosol] (Caenorhabditis elegans)

PARD6B [cytosol] (Gallus gallus)

PARD6B [cytosol] (Sus scrofa)

PARD6B [cytosol] (Xenopus tropicalis)

par-6 [cytosol] (Caenorhabditis elegans)

par-6 [cytosol] (Drosophila melanogaster)

Homologues of PARD6B [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_115910.1

OpenTargets

ENSG00000124171

HPA

ENSG00000124171-PARD6B

GeneCards

Q9BYG5

Ensembl

ENSG00000124171, ENST00000371610, ENSP00000360672, ENST00000396039, ENSP00000379354

PRO

Q9BYG5

Pharos - Targets

Q9BYG5

HMDB Protein

HMDBP08501

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41743 PRKCI	3	PRKCI [cytosol] (R-HSA-58206) PRKCI [nucleoplasm] (R-HSA-9021345) PRKCI [plasma membrane] (R-HSA-420005)	0.954	22
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181)	0.935	13
UniProt:P60953 CDC42	3	CDC42 [plasma membrane] (R-HSA-449545) CDC42 [cytosol] (R-HSA-442630) CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086)	0.896	18
UniProt:P63000 RAC1	6	RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [cytosol] (R-HSA-442615) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) RAC1 [plasma membrane] (R-HSA-351141)	0.567	3
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179)	0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [cytosol] (R-HSA-162411) TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3