Trafficking of GluR2-containing AMPA receptors to synapse

Stable Identifier
R-HSA-416985
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Constitutively recycling GluR2 containing AMPA receptors in the plasma membrane are stabilized by the action of NSF ATPase activity which disassociates PICK from GluR2 thereby retaining AMPA receptors in the plasma membrane.

Literature References
PubMed ID Title Journal Year
16055064 PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking

Lu, W, Ziff, EB

Neuron 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ATPase activity of NSF [cytosol]
Physical Entity
Activity
This event is regulated
Orthologous Events
Authored
Reviewed
Created