Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PLC beta1,2,3 [cytosol]
Stable Identifier
R-HSA-400005
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Phospholipase C Beta (pancreatic beta cell)
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Acetylcholine regulates insulin secretion (Homo sapiens)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
Gq alpha activates Phospholipase C beta (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
Free fatty acids regulate insulin secretion (Homo sapiens)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
Gq alpha activates Phospholipase C beta (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Homo sapiens)
PLC beta1,2,3 [cytosol] (Homo sapiens)
General
Pancreatic beta cells contain PLC Beta 1, PLC Beta 2, and PLC Beta 3. It is unknown which PLC or combination of PLC's are activated in response to G(q).
Participants
candidates
PLCB1 [cytosol]
(Homo sapiens)
PLCB2 [cytosol]
(Homo sapiens)
PLCB3 [cytosol]
(Homo sapiens)
Participates
as an input of
Gq alpha activates Phospholipase C beta (Homo sapiens)
as a component of
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Homo sapiens)
Inferred To
PLC beta1,2,3 [cytosol]
(Bos taurus)
PLC beta1,2,3 [cytosol]
(Canis familiaris)
PLC beta1,2,3 [cytosol]
(Dictyostelium discoideum)
PLC beta1,2,3 [cytosol]
(Drosophila melanogaster)
PLC beta1,2,3 [cytosol]
(Gallus gallus)
PLC beta1,2,3 [cytosol]
(Mus musculus)
PLC beta1,2,3 [cytosol]
(Rattus norvegicus)
PLC beta1,2,3 [cytosol]
(Saccharomyces cerevisiae)
PLC beta1,2,3 [cytosol]
(Schizosaccharomyces pombe)
PLC beta1,2,3 [cytosol]
(Sus scrofa)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text