The Gq alpha:GTP complex activates Phospholipase C beta-1 through protein interaction (inferred from homologues in Bos taurus). The activation by Gq alpha is insensitive to pertussis toxin whilst activation of PLC beta by the G beta-gamma complex is sensitive to pertussis toxin.
Smrcka, AV, Sternweis, PC, Hepler, JR, Brown, KO
Ahren, B, Winzell, MS
Gilon, P, Henquin, JC
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