Reactome | ADRA2A,B,C:ADR,NAd [plasma membrane]

ADRA2A,B,C:ADR,NAd [plasma membrane]

Stable Identifier

R-HSA-390700

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Alpha-2 adrenoceptor:Catecholamine

Locations in the PathwayBrowser

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Participants

components

Participates

as an output of

ADRA2A,B,C bind ADR,NAd (Homo sapiens)

as an input of

Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Homo sapiens)

as a component of

Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Homo sapiens)
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Homo sapiens)

as a member of

Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)

Inferred To

ADRA2A,B,C:ADR,NAd [plasma membrane] (Bos taurus)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Caenorhabditis elegans)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Canis familiaris)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Danio rerio)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Drosophila melanogaster)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Gallus gallus)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Mus musculus)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Rattus norvegicus)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Sus scrofa)

ADRA2A,B,C:ADR,NAd [plasma membrane] (Xenopus tropicalis)

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