FAR1 reduces PalmCoA to HXOL

Stable Identifier
R-HSA-390425
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1]
Locations in the PathwayBrowser
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Peroxisomal fatty acyl-CoA reductase 1 (FAR1) catalyzes the reaction of palmitoyl-CoA (PalmCoA) and 2 NADPH + 2 H+ to form hexadecanol (HXOL), CoASH, and 2 NADP+. As judged from mRNA levels, FAR1 is widely expressed in the body (Cheng and Russell 2004).

Literature References
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
oxidoreductase activity of FAR1 [peroxisomal membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created