Reactome | FAR1 [peroxisomal membrane]

FAR1 [peroxisomal membrane]

Stable Identifier

R-HSA-390412

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal membrane

Synonyms

Fatty acyl-CoA reductase 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WVX9 FAR1

Gene Names

FAR1, MLSTD2, UNQ2423/PRO4981

Chain

chain:1-515

Reference Genes

BioGPS Gene:84188 FAR1

COSMIC (genes):FAR1 FAR1

CTD Gene:84188 FAR1

dbSNP Gene:84188 FAR1

ENSEMBL:ENSG00000197601 FAR1

ENSEMBL_homo_sapiens_GENE:ENSG00000197601.14 FAR1

HGNC:26222 FAR1

KEGG Gene (Homo sapiens):84188 FAR1

Monarch:84188 FAR1

NCBI Gene:84188 FAR1

OMIM:616107 FAR1

UCSC:Q8WVX9 FAR1

Reference Transcript

RefSeq:NM_032228.5 FAR1

Other Identifiers

11734734_s_at

11734735_a_at

11734736_a_at

11734737_a_at

1558014_PM_s_at

1558014_s_at

16722252

224865_PM_at

224865_at

224866_PM_at

224866_at

3321270

3321271

3321272

3321273

3321283

3321284

3321291

3321292

3321296

3321298

3321301

3321303

3321310

3321311

3321313

3321315

3321316

3321317

3321318

3321319

3321320

3321321

3321322

3496219

3496222

3496224

46265_at

63614_r_at

76263_at

7938592

84188

87469_at

A_23_P339554

A_23_P339557

A_24_P163920

A_24_P278460

GE79785

GO:0003824

GO:0005515

GO:0005777

GO:0005778

GO:0006629

GO:0006790

GO:0008611

GO:0010025

GO:0016020

GO:0016491

GO:0035336

GO:0043226

GO:0046474

GO:0055086

GO:0080019

GO:0102965

GO:1901135

GO:1901568

HMNXSV003037844

Hs.288368.0.A1_3p_at

Hs.288368.0.A2_3p_at

Hs2.418339.1.S1_3p_s_at

ILMN_2143250

PH_hs_0014960

PH_hs_0032515

TC11000208.hg

Inferred To

anon-WO0140519.58 [peroxisomal membrane] (Drosophila melanogaster)

fard-1 [peroxisomal membrane] (Caenorhabditis elegans)

CG18680 [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG4770 [peroxisomal membrane] (Drosophila melanogaster)

FAR1 [peroxisomal membrane] (Bos taurus)

FAR1 [peroxisomal membrane] (Canis familiaris)

FAR1 [peroxisomal membrane] (Dictyostelium discoideum)

FAR1 [peroxisomal membrane] (Drosophila melanogaster)

FAR1 [peroxisomal membrane] (Gallus gallus)

FAR1 [peroxisomal membrane] (Sus scrofa)

Dmel\CG12268 [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG17562 [peroxisomal membrane] (Drosophila melanogaster)

CG32422 [peroxisomal membrane] (Drosophila melanogaster)

CT34717 [peroxisomal membrane] (Drosophila melanogaster)

Homologues of FAR1 [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG17560 [peroxisomal membrane] (Drosophila melanogaster)

wat [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG4020 [peroxisomal membrane] (Drosophila melanogaster)

Sgp [peroxisomal membrane] (Drosophila melanogaster)

FarO [peroxisomal membrane] (Drosophila melanogaster)

CG32919 [peroxisomal membrane] (Drosophila melanogaster)

Far1 [peroxisomal membrane] (Mus musculus)

Far1 [peroxisomal membrane] (Rattus norvegicus)

Dmel\CG1441 [peroxisomal membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_115604.1

OpenTargets

ENSG00000197601

IntEnz

1.2.1.84

HPA

ENSG00000197601-FAR1

GeneCards

Q8WVX9

Ensembl

ENSG00000197601, ENST00000354817, ENSP00000346874

PRO

Q8WVX9

Pharos - Targets

Q8WVX9

Orphanet

23530

HMDB Protein

HMDBP07270

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96A83-2 Q96A832			0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	9

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