Reactome | FAR1 [peroxisomal membrane]

FAR1 [peroxisomal membrane]

Stable Identifier

R-HSA-390412

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal membrane

Synonyms

Fatty acyl-CoA reductase 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WVX9 FAR1

Gene Names

FAR1, MLSTD2, UNQ2423/PRO4981

Chain

chain:1-515

Reference Genes

BioGPS Gene:84188 FAR1

COSMIC (genes):FAR1 FAR1

CTD Gene:84188 FAR1

dbSNP Gene:84188 FAR1

ENSEMBL:ENSG00000197601 FAR1

HGNC:26222 FAR1

KEGG:hsa:84188 FAR1

Monarch:84188 FAR1

NCBI Gene:84188 FAR1

OMIM:616107 FAR1

UCSC:Q8WVX9 FAR1

Reference Transcript

RefSeq:NM_032228.6 FAR1

Other Identifiers

11734734_s_at

11734735_a_at

11734736_a_at

11734737_a_at

1558014_PM_s_at

1558014_s_at

16722252

224865_PM_at

224865_at

224866_PM_at

224866_at

3321270

3321271

3321272

3321273

3321283

3321284

3321285

3321291

3321292

3321293

3321294

3321295

3321296

3321297

3321298

3321299

3321301

3321302

3321303

3321304

3321308

3321309

3321310

3321311

3321313

3321315

3321316

3321317

3321318

3321319

3321320

3321321

3321322

3496219

3496222

3496224

46265_at

63614_r_at

76263_at

7938592

84188

87469_at

A_23_P2032

A_23_P339554

A_23_P339557

A_24_P163920

A_24_P278460

GE693099

GE79785

GO:0003824

GO:0005515

GO:0005777

GO:0005778

GO:0006629

GO:0006790

GO:0008611

GO:0010025

GO:0016020

GO:0016491

GO:0035336

GO:0043226

GO:0046474

GO:0055086

GO:0080019

GO:0102965

GO:1901135

GO:1901568

HMNXSV003037844

Hs.288368.0.A1_3p_at

Hs.288368.0.A2_3p_at

Hs2.418339.1.S1_3p_s_at

ILMN_2143250

PH_hs_0014960

PH_hs_0032515

TC11000208.hg

Inferred To

anon-WO0140519.58 [peroxisomal membrane] (Drosophila melanogaster)

fard-1 [peroxisomal membrane] (Caenorhabditis elegans)

CG18680 [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG4770 [peroxisomal membrane] (Drosophila melanogaster)

FAR1 [peroxisomal membrane] (Bos taurus)

FAR1 [peroxisomal membrane] (Canis familiaris)

FAR1 [peroxisomal membrane] (Dictyostelium discoideum)

FAR1 [peroxisomal membrane] (Drosophila melanogaster)

FAR1 [peroxisomal membrane] (Gallus gallus)

FAR1 [peroxisomal membrane] (Sus scrofa)

Dmel\CG12268 [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG17562 [peroxisomal membrane] (Drosophila melanogaster)

CG32422 [peroxisomal membrane] (Drosophila melanogaster)

CT34717 [peroxisomal membrane] (Drosophila melanogaster)

Homologues of FAR1 [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG17560 [peroxisomal membrane] (Drosophila melanogaster)

wat [peroxisomal membrane] (Drosophila melanogaster)

Dmel\CG4020 [peroxisomal membrane] (Drosophila melanogaster)

Sgp [peroxisomal membrane] (Drosophila melanogaster)

FarO [peroxisomal membrane] (Drosophila melanogaster)

CG32919 [peroxisomal membrane] (Drosophila melanogaster)

Far1 [peroxisomal membrane] (Mus musculus)

Far1 [peroxisomal membrane] (Rattus norvegicus)

Dmel\CG1441 [peroxisomal membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_115604.1

ENSEMBL

ENST00000354817, ENSG00000197601, ENSP00000346874

OpenTargets

ENSG00000197601

IntEnz

1.2.1.84

GeneCards

FAR1

HPA

ENSG00000197601-FAR1

PRO

Q8WVX9

Pharos - Targets

Q8WVX9

Orphanet

FAR1

HMDB Protein

HMDBP07270

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96A83-2 Q96A832			0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	9

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