Reactome | SRMS [cytosol]

SRMS [cytosol]

Stable Identifier

R-HSA-3902520

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Tyrosine-protein kinase Srms ecNumber2.7.10.2/ecNumber, SRMS_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H3Y6 SRMS

Gene Names

SRMS, C20orf148

Chain

chain:1-488

Reference Genes

BioGPS Gene:6725 SRMS

COSMIC (genes):SRMS SRMS

CTD Gene:6725 SRMS

dbSNP Gene:6725 SRMS

ENSEMBL:ENSG00000125508 SRMS

HGNC:11298 SRMS

KEGG:hsa:6725 SRMS

Monarch:6725 SRMS

NCBI Gene:6725 SRMS

OMIM:617797 SRMS

UCSC:Q9H3Y6 SRMS

Reference Transcript

RefSeq:NM_080823.3 SRMS

Other Identifiers

11741534_at

16921280

234514_PM_at

234514_at

3913940

3913941

3913942

3913944

3913946

3913947

3913948

3913950

3913952

3913954

3913955

3913956

3913957

3913958

3913959

6725

8067671

A_23_P68380

A_33_P3236798

GO:0002376

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005102

GO:0005515

GO:0005524

GO:0005737

GO:0005829

GO:0005886

GO:0006468

GO:0007169

GO:0009968

GO:0016740

GO:0018108

GO:0030154

GO:0038083

GO:0045087

GO:0098542

GO:0140096

GO:1904263

HMNXSV003023819

Hs.302093.0.S1_3p_at

ILMN_1744200

PH_hs_0024856

TC20001034.hg

Inferred To

SRMS [cytosol] (Bos taurus)

SRMS [cytosol] (Caenorhabditis elegans)

SRMS [cytosol] (Mus musculus)

SRMS [cytosol] (Rattus norvegicus)

SRMS [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_543013.1

ZINC - World Drugs

SRMS_HUMAN

Guide to Pharmacology - Targets

2207

ENSEMBL

ENST00000217188, ENSP00000217188

OpenTargets

ENSG00000125508

ZINC - FDA approved

SRMS_HUMAN

ZINC - Substances

SRMS_HUMAN

ZINC - Biogenic

SRMS_HUMAN

ZINC target

Q9H3Y6

PRO

Q9H3Y6

ZINC - Investigational

SRMS_HUMAN

IntEnz

2.7.10.2

HPA

ENSG00000125508-SRMS

Pharos - Targets

Q9H3Y6

ZINC - Predictions - Purchasable

SRMS_HUMAN

HMDB Protein

HMDBP01510

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99704 DOK1	2	p-Y362-DOK1 [cytosol] (R-HSA-8848784) DOK1 [cytosol] (R-HSA-74763)	0.639	7
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.556	3
UniProt:Q58FF6 H90B4			0.527	3
UniProt:Q9H078 CLPB			0.527	2
UniProt:P08238 HSP90AB1	6	HSP90AB1 [lysosomal lumen] (R-HSA-9622846) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491)	0.527	3
UniProt:Q13451 FKBP5	2	FKBP5 [nucleoplasm] (R-HSA-8939165) FKBP5 [cytosol] (R-HSA-5618096)	0.527	3
UniProt:P07900 HSP90AA1	8	HSP90AA1 [lysosomal lumen] (R-HSA-9622850) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912)	0.527	3
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.527	3

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