F2RL1(37-397)

Stable Identifier
R-HSA-389418
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Proteinase-activated receptor 2, RecName: Full=Proteinase-activated receptor 2; Short=PAR-2; AltName: Full=Thrombin receptor-like 1; AltName: Full=Coagulation factor II receptor-like 1; AltName: Full=G-protein coupled receptor 11; Flags: Precursor;
GN Name=F2RL1; Synonyms=GPR11, PAR2;
OS Homo sapiens, PAR2_HUMAN, F2RL1
Locations in the PathwayBrowser
Summation

This is the inactive form of the receptor, before protease activation. Proteinase (protease) activated receptors are activated by the cleavage of an N-terminal extracellular segment by serine proteases, particularly thrombin which activates PAR1, 3 and 4. The cleaved fragment is an activating ligand for the receptor; synthetic peptide mimics of the N-terminal fragment can activate uncleaved receptors.

External Reference Information
External Reference
Gene Names
F2RL1, GPR11, PAR2
Chain
signal peptide:1-25, propeptide:26-36, chain:37-397, chain:38-397, chain:39-397
Reference Transcript
Other Identifiers
0001190411
11728827_at
11728828_at
12989
14091
16986417
206429_at
213506_at
2150
2816495
2816496
2816498
2816499
36344_at
36345_g_at
38247_at
8106403
A_14_P117888
A_23_P58835
A_33_P3232945
CCDS4033
D6RJH3
ENSG00000164251
ENSP00000296677
ENST00000296677
EntrezGene:2150
F2RL1
F2RL1-201
g8051581_3p_at
GE59346
GO:0001965
GO:0002286
GO:0002376
GO:0002690
GO:0002741
GO:0003013
GO:0003104
GO:0003674
GO:0004871
GO:0004930
GO:0005102
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005768
GO:0005769
GO:0005794
GO:0005886
GO:0005887
GO:0006464
GO:0006810
GO:0006950
GO:0006954
GO:0007010
GO:0007165
GO:0007186
GO:0007204
GO:0007596
GO:0008150
GO:0008283
GO:0009058
GO:0010804
GO:0014068
GO:0015057
GO:0016020
GO:0016021
GO:0016192
GO:0022607
GO:0030154
GO:0030193
GO:0030335
GO:0030836
GO:0031143
GO:0031274
GO:0031410
GO:0031681
GO:0032930
GO:0034137
GO:0034140
GO:0034141
GO:0034145
GO:0034330
GO:0034641
GO:0035025
GO:0035926
GO:0038023
GO:0040011
GO:0042119
GO:0042592
GO:0043122
GO:0043123
GO:0043226
GO:0043311
GO:0043547
GO:0044403
GO:0045087
GO:0045217
GO:0045944
GO:0046328
GO:0046329
GO:0046330
GO:0048856
GO:0048870
GO:0050702
GO:0050900
GO:0050921
GO:0050927
GO:0051482
GO:0051607
GO:0060100
GO:0061024
GO:0061028
GO:0070374
GO:0070493
GO:0070661
GO:0070963
GO:0072608
GO:0072643
GO:0090195
GO:0090198
GO:0097029
GO:0097755
GO:1900135
GO:2000484
GO:2000778
HGNC:3538
Hs.168102.0.S1_3p_at
ILMN_1673113
ILMN_2041190
IPR000276
IPR002281
IPR003912
IPR017452
MIM:600933
NM_005242
NP_005233
PF00001
PH_hs_0009290
PR00237
PR01152
PR01428
TC05000372.hg
TC05002459.hg
U34038_at
uc003keo.4
UPI000013E36E
XM_017009223
XP_016864712
Participant Of
Inferred To
Cross References
RefSeq
ZINC - Substances
GeneCards
ZINC target
ZINC - Biogenic
PRO
ZINC - Predictions - Purchasable
Orphanet
PDB