Tachykinin receptor 2 (NK2) binds to nuerokinin A

Stable Identifier
R-HSA-383363
Type
Reaction [binding]
Species
Homo sapiens
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Neurokinin A (substance K) (Gerard NP et al, 1990) is a peptide neurotransmitter of the tachykinin family which can act as a mediator in human airway and gastrointestinal tissues. Neurokinin A acts via the substance K receptor (NK-2 receptor) (Harmar AJ et al, 1986), believed to be localized on smooth muscle cells and pharmacologically coupled to a GTP-binding protein.

Literature References
PubMed ID Title Journal Year
3770210 cDNA sequence of human beta-preprotachykinin, the common precursor to substance P and neurokinin A

Harmar, AJ, Armstrong, A, Pascall, JC, Chapman, K, Rosie, R, Curtis, A, Going, J, Edwards, CR, Fink, G

FEBS Lett 1986
2173708 The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues

Gerard, NP, Eddy, RL, Shows, TB, Gerard, C

J Biol Chem 1990
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